Nitrendipine

Cat. No. 0601

Nitrendipine C18H20N2O6 [39562-70-4]

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Chemical Name: 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridine dicarboxylic acid ethyl methyl ester

Biological Activity

L-type calcium channel blocker.

Technical Data

M.Wt:
360.37
Formula:
C18H20N2O6
Solubility:
Soluble to 50 mM in DMSO and to 25 mM in ethanol
Purity:
>99 %
Storage:
Store at RT
CAS No:
39562-70-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Fleming et al (2011) Chemical modulators of autophagy as biological probes and potential therapeutics. Nat.Chem.Biol. 7 9. PMID: 21164513.

Costa et al (1996) Characterization of a voltage-dependent L-type calcium channel from rabbit and turtle brain. Neurochem.Res. 21 537. PMID: 8726959.

Watanabe et al (1995) L-type calcium channel block by highly hydrophilic dihydropyridines in single ventricular cells of guinea-pig hearts. J.Mol.Cell.Cardiol. 27 1271. PMID: 8531209.

Merck Index 12 6667.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for Nitrendipine include:

Subramanian and Morozov (2011) Erk1/2 inhibit synaptic vesicle exocytosis through L-type calcium channels. J Neurosci 31 4755. PMID: 21430174.

Rosenkranz et al (2009) Regulation of protease-activated receptor-1 by vasodilatory prostaglandins via NFAT. Cardiovasc Res 83 778. PMID: 19460777.

Do you know of a great paper that uses Nitrendipine from Tocris? If so please let us know.

View Related Products by Product Action

Keywords: Nitrendipine, supplier, Ca2+, channel, blockers, L-type, Calcium, CaV, Channels, voltage-gated, voltage-dependent, Tocris Bioscience, Voltage-gated Calcium Channel (CaV) Blocker products

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