Cat. No. 0800

7-NINA C7H4N3O2Na [161467-34-1]

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Chemical Name: 7-Nitroindazole monosodium salt

Biological Activity

Sodium salt of the non-selective NOS inhibitor 7-nitroindazole (Cat. No. 0602).

Technical Data

Soluble to 2 mM in water and to 50 mM in DMSO
>98 %
Desiccate at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

O'Neill et al (1996) Neuroprotective effects of 7-nitroindazole in the gerbil model of global cerebral ischaemia. Eur.J.Pharmacol. 310 115. PMID: 8884206.

Silva et al (1995) Increased striatal dopamine efflux in vivo following inhibition of cerebral nitric oxide synthase by the novel monosodium salt of 7-nitroindazole. Br.J.Pharmacol. 114 257. PMID: 7533610.

If you know of a relevant reference for 7-NINA please let us know.

Citations are publications that use Tocris products. Selected citations for 7-NINA include:

Fakira et al (2012) Purkinje cell dysfunction and delayed death in plasma membrane calcium ATPase 2-heterozygous mice. J Neurosci 51 22. PMID: 22789621.

Messlinger et al (2000) Involvement of nitric oxide in the modulation of dural arterial blood flow in the rat. Br J Pharmacol 129 1397. PMID: 10742295.

Do you know of a great paper that uses 7-NINA from Tocris? If so please let us know.

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Keywords: 7-NINA, supplier, Non-Selective, NOS, Nitric, Oxide, Signaling, Signalling, iNOS, nNOS, eNOS, NO, Synthases, Tocris Bioscience, Non-selective NOS Inhibitor products

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