Nicergoline

Cat. No. 0604

Nicergoline C24H26BrN3O3 [27848-84-6]

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Chemical Name: (8β)-10-methoxy-1,6-dimethylergoline-8-methanol 5-bromo-3-pyridine carboxylate ester

Biological Activity

α-adrenergic, vasodilator. Cognitive enhancer.

Technical Data

M.Wt:
484.39
Formula:
C24H26BrN3O3
Solubility:
Soluble to 100 mM in DMSO
Storage:
Store at RT
CAS No:
27848-84-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Carfagna et al (1996) Modulation of phosphoinositide turnover by chronic nicergoline in rat brain. Neurosci.Lett. 209 189. PMID: 8736642.

Carfagna et al (1995) Modulation of hippocampal ACh release by chronic nicergoline treatment in freely moving young and aged rats. Neurosci.Lett. 197 195. PMID: 8552297.

Chopin and Briley (1992) Effects of four non-cholinergic cognitive enhancers in comparison with tacrine and galanthamine on scopolamine-induced amnesia in rats. Psychopharmacology 106 26. PMID: 1738791.

Merck Index 12 6580.

If you know of a relevant reference for Nicergoline please let us know.

Citations are publications that use Tocris products. Selected citations for Nicergoline include:

Woo et al (2007) Neuregulin-1 enhances depolarization-induced GABA release. Neuron 54 599. PMID: 17521572.

Do you know of a great paper that uses Nicergoline from Tocris? If so please let us know.

Keywords: Nicergoline, supplier, α-adrenoceptor, alpha-adrenoceptor, a-adrenoceptor, antagonists, α-adrenergic, alpha-adrenergic, a-adrenergic, Receptors, Non-Selective, vasodilator, Tocris Bioscience, Non-selective Adrenergic α Receptor Antagonist products

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