Cat. No. 0780

NCS-382 C13H14O3 [520505-01-5]

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Chemical Name: 6,7,8,9-Tetrahydro-5-hydroxy-5H-benzocyclohept-6-ylideneacetic acid

Biological Activity

γ-Hydroxybutyric acid antagonist, anticonvulsant.

Technical Data

Soluble to 100 mM in DMSO
>99 %
Desiccate at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

Certificate of Analysis is currently unavailable
on-line. Please contact Customer Service

References are publications that support the products' biological activity.

King et al (1997) Gammahydroxybutyrate (GHB) receptor ligand effects on evoked synaptic field potentials in CA1 of the rat hippocampal slice. J.Neural Transm. 104 1177. PMID: 9503264.

Schmidt et al (1991) Anti-sedative and anti-cataleptic properties of NCS-382, a γ-hydroxybutyrate receptor antagonist. Eur.J.Pharmacol. 203 393. PMID: 1773824.

Maitre et al (1990) A specific γ-hydroxybutyrate receptor ligand possesses both antagonist and anticonvulsant properties. J.Pharmacol.Exp.Ther. 255 657. PMID: 2173754.

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Citations are publications that use Tocris products.

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Keywords: NCS-382, supplier, antagonists, γ-hydroxybutyric, gamma-hydroxybutyric, acid, GABAA, GABAC, Receptors, GABAB, anticonvulsant, Tocris Bioscience, Miscellaneous GABA products

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