NBQX

Cat. No. 0373

NBQX C12H8N4O6S [118876-58-7]

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Chemical Name: 2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide

Biological Activity

Potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo. NBQX disodium salt (Cat. No. 1044) also available.

Licensing Information

Sold with the permission of Novo Nordisk A/S

Technical Data

M.Wt:
336.28
Formula:
C12H8N4O6S
Solubility:
Soluble to 100 mM in DMSO
Purity:
>98 %
Storage:
Store at RT
CAS No:
118876-58-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Certificate of Analysis / Product Datasheet
Select another batch:

Namba et al (1994) Antiepileptogenic and anticonvulsant effects of NBQX, a selective AMPA receptor antagonist, in the rat kindling model of epilepsy. Brain Res. 638 36. PMID: 8199874.

Sheardown et al (1993) The pharmacology of AMPA receptors and their antagonists. Stroke 24 146. PMID: 7504337.

Gill et al (1992) The neuroprotective actions of 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(f)quinoxaline (NBQX) in a rat focal ischaemia model. Brain Res. 580 35. PMID: 1504814.

Zeman and Lodge (1992) Pharmacological characterization of non-NMDA subtypes of glutamate receptors in the neonatal rat hemisected spinal cord in vitro. Br.J.Pharmacol. 106 367. PMID: 1382781.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for NBQX include:

Delaney and Crane (2016) Presynaptic GABAB receptors reduce transmission at parabrachial synapses in the lateral central amygdala by inhibiting N-type calcium channels. Sci Rep 6 19255. PMID: 26755335.

Dennis et al (2016) Activation of Muscarinic M1 Acetylcholine Receptors Induces Long-Term Potentiation in the Hippocampus. J Neurosci 26 414. PMID: 26472558.

Chen et al (2015) AMPA Receptor-mTOR Activation is Required for the Antidepressant-Like Effects of Sarcosine during the Forced Swim Test in Rats: Insertion of AMPA Receptor may Play a Role. Front Behav Neurosci 9 162. PMID: 26150775.

Duménieu et al (2015) Afterhyperpolarization (AHP) regulates the frequency and timing of action potentials in the mitral cells of the olfactory bulb: role of olfactory experience. Sci Rep 3. PMID: 26019289.

Ghosh et al (2015) Norepinephrine Modulates Pyramidal Cell Synaptic Properties in the Anterior Piriform Cortex of Mice: Age-Dependent Effects of β-adrenoceptors. Proc Natl Acad Sci U S A 9 450. PMID: 26635530.

Grimes et al (2015) A simple retinal mechanism contributes to perceptual interactions between rod- and cone-mediated responses in primates. Elife 4. PMID: 26098124.

Hirono et al (2015) BK Channels Localize to the Paranodal Junction and Regulate Action Potentials in Myelinated Axons of Cerebellar Purkinje Cells. Brain Res 35 7082. PMID: 25948259.

Hooks et al (2015) Dual-channel circuit mapping reveals sensorimotor convergence in the primary motor cortex. Front Cell Neurosci 35 4418. PMID: 25762684.

Iskandrani et al (2015) Impact of subanesthetic doses of ketamine on AMPA-mediated responses in rats: An in vivo electrophysiological study on monoaminergic and glutamatergic neurons. Stroke 29 792. PMID: 25759403.

John et al (2015) Functional α7 nicotinic receptors are expressed on immature granule cells of the postnatal dentate gyrus. J Neurosci 1601 15. PMID: 25553616.

Kardamakis et al (2015) Tectal microcircuit generating visual selection commands on gaze-controlling neurons. J Neurosci 112 E1956. PMID: 25825743.

Laprell et al (2015) Optical control of NMDA receptors with a diffusible photoswitch. Front Cell Neurosci 6 8076. PMID: 26311290.

Lee et al (2015) Activation of corticostriatal circuitry relieves chronic neuropathic pain. Physiol Rep 35 5247. PMID: 25834050.

Mapelli et al (2015) The effect of desflurane on neuronal communication at a central synapse. Nat Commun 10 e0123534. PMID: 25849222.

Marciniak et al (2015) The Chemokine MIP-1α/CCL3 impairs mouse hippocampal synaptic transmission, plasticity and memory. Front Synaptic Neurosci 5 15862. PMID: 26511387.

Pasca et al (2015) Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture. Front Cell Neurosci 12 671. PMID: 26005811.

Perissinotti et al (2015) Calcium current homeostasis and synaptic deficits in hippocampal neurons from Kelch-like 1 knockout mice. Elife 8 444. PMID: 25610372.

Saunders et al (2015) Corelease of acetylcholine and GABA from cholinergic forebrain neurons. Cereb Cortex 4. PMID: 25723967.

Sheng et al (2015) Involvement of adrenoceptors, dopamine receptors and AMPA receptors in antidepressant-like action of 7-O-ethylfangchinoline in mice. Acta Pharmacol Sin 36 949. PMID: 26238289.

Sobieski et al (2015) Loss of Local Astrocyte Support Disrupts Action Potential Propagation and Glutamate Release Synchrony from Unmyelinated Hippocampal Axon Terminals In Vitro. PLoS One 35 11105. PMID: 26245971.

Zimmermann et al (2015) Co-release of glutamate and GABA from single vesicles in GABAergic neurons exogenously expressing VGLUT3. J Neurosci 7 16. PMID: 26441632.

Ady et al (2014) Type 1 metabotropic glutamate receptors (mGlu1) trigger the gating of GluD2 δ glutamate receptors. Proc Natl Acad Sci U S A 15 103. PMID: 24357660.

Bemben et al (2014) CaMKII phosphorylation of neuroligin-1 regulates excitatory synapses. Nat Neurosci 17 56. PMID: 24336150.

Cunningham et al (2014) hPSC-derived maturing GABAergic interneurons ameliorate seizures and abnormal behavior in epileptic mice. Cell Stem Cell 15 559. PMID: 25517465.

Grimes et al (2014) Cross-synaptic synchrony and transmission of signal and noise across the mouse retina. Elife 3 e03892. PMID: 25180102.

Halff et al (2014) A novel mechanism for nicotinic potentiation of glutamatergic synapses. J Neurosci 34 2051. PMID: 24501347.

Ivanov et al (2014) Glycolysis and oxidative phosphorylation in neurons and astrocytes during network activity in hippocampal slices. J Cereb Blood Flow Metab 34 397. PMID: 24326389.

Leitz and Kavalali (2014) Fast retrieval and autonomous regulation of single spontaneously recycling synaptic vesicles. Elife 3 e03658. PMID: 25415052.

Ostrowski et al (2014) Depressed GABA and glutamate synaptic signaling by 5-HT1A receptors in the nucleus tractus solitarii and their role in cardiorespiratory function. J Neurophysiol 111 2493. PMID: 24671532.

Pollard et al (2014) Modulation of neuronal microcircuit activities within the medial prefrontal cortex by mGluR5 positive allosteric modulator. J Psychopharmacol 28 935. PMID: 25031220.

Suzuki et al (2014) Imaging intraorganellar Ca2+ at subcellular resolution using CEPIA. Nat Commun 5 4153. PMID: 24923787.

Vaghi et al (2014) Rac1 and rac3 GTPases control synergistically the development of cortical and hippocampal GABAergic interneurons. Cereb Cortex 24 1247. PMID: 23258346.

Varodayan and Harrison (2014) HSF1 transcriptional activity mediates alcohol induction of Vamp2 expression and GABA release. J Neurosci 7 89. PMID: 24376402.

Wilcox et al (2014) Repeated binge-like ethanol drinking alters ethanol drinking patterns and depresses striatal GABAergic transmission. Neuropsychopharmacology 39 579. PMID: 23995582.

Akrouh and Kerschensteiner (2013) Intersecting circuits generate precisely patterned retinal waves. Neuron 79 322. PMID: 23830830.

Alpert and (2013) Synaptic NMDA receptor-dependent Ca2+ entry drives membrane potential and Ca2+ oscillations in spinal ventral horn neurons. PLoS One 8 e63154. PMID: 23646190.

Bonnet et al (2013) AMPA/kainate glutamate receptors contribute to inflammation, degeneration and pain related behaviour in inflammatory stages of arthritis. Ann Rheum Dis. PMID: 24130267.

Brady et al (2013) Moderate prenatal alcohol exposure reduces plasticity and alters NMDA receptor subunit composition in the dentate gyrus. Proc Natl Acad Sci U S A 33 1062. PMID: 23325244.

Hamida et al (2013) Protein tyrosine phosphatase α in the dorsomedial striatum promotes excessive ethanol-drinking behaviors. Nat Neurosci 33 14369. PMID: 24005290.

Hou and Yu (2013) Activity-regulated somatostatin expression reduces dendritic spine density and lowers excitatory synaptic transmission via postsynaptic somatostatin receptor 4. J Biol Chem 288 2501. PMID: 23233668.

Malmersjö et al (2013) Neural progenitors organize in small-world networks to promote cell proliferation. J Neurosci 110 E1524. PMID: 23576737.

Pooler et al (2013) Physiological release of endogenous tau is stimulated by neuronal activity. J Neuroimmunol 14 389. PMID: 23412472.

Rompala et al (2013) Contribution of NMDA receptor hypofunction in prefrontal and cortical excitatory neurons to schizophrenia-like phenotypes. J Neurosci 8 e61278. PMID: 23613827.

Selvakumar et al (2013) S-nitrosylation of AMPA receptor GluA1 regulates phosphorylation, single-channel conductance, and endocytosis. Proc Natl Acad Sci U S A 110 1077. PMID: 23277581.

Song et al (2013) Different transporter systems regulate extracellular GABA from vesicular and non-vesicular sources. Front Cell Neurosci 7 23. PMID: 23494150.

Ufartes et al (2013) Behavioural and functional characterization of Kv10.1 (Eag1) knockout mice. Hum Mol Genet 22 2247. PMID: 23424202.

Woo et al (2013) The adhesion protein IgSF9b is coupled to neuroligin 2 via S-SCAM to promote inhibitory synapse development. J Cell Biol 201 929. PMID: 23751499.

Cassé et al (2012) Glutamate controls tPA recycling by astrocytes, which in turn influences glutamatergic signals. J Neurosci 32 5186. PMID: 22496564.

Chacón et al (2012) Focal adhesion kinase regulates actin nucleation and neuronal filopodia formation during axonal growth. Dev Neurobiol 139 3200. PMID: 22872087.

Crawford et al (2012) Differential requirement for protein synthesis in presynaptic unmuting and muting in hippocampal glutamate terminals. PLoS One 7 e51930. PMID: 23272190.

Daftary et al (2012) Essential role of brain-derived neurotrophic factor in the regulation of serotonin transmission in the basolateral amygdala. Neuroscience 224 125. PMID: 22917617.

Dubos et al (2012) Alteration of synaptic network dynamics by the intellectual disability protein PAK3. Eur J Neurosci 32 519. PMID: 22238087.

Jacus et al (2012) Presynaptic Cav3.2 channels regulate excitatory neurotransmission in nociceptive dorsal horn neurons. Proc Natl Acad Sci U S A 32 9374. PMID: 22764245.

Lethbridge et al (2012) Olfactory bulb glomerular NMDA receptors mediate olfactory nerve potentiation and odor preference learning in the neonate rat. J Neurosci 7 e35024. PMID: 22496886.

Mitra et al (2012) Heterogeneous reallocation of presynaptic efficacy in recurrent excitatory circuits adapting to inactivity. Nat Neurosci 15 250. PMID: 22179109.

Nebieridze et al (2012) β-Estradiol unmasks metabotropic receptor-mediated metaplasticity of NMDA receptor transmission in the female rat dentate gyrus. Psychoneuroendocrinology 37 1845. PMID: 22541715.

Nelson and Glitsch (2012) Lack of kinase regulation of canonical transient receptor potential 3 (TRPC3) channel-dependent currents in cerebellar Purkinje cells. PLoS One 287 6326. PMID: 22207762.

Thoeringer et al (2012) Consolidation of remote fear memories involves Corticotropin-Releasing Hormone (CRH) receptor type 1-mediated enhancement of AMPA receptor GluR1 signaling in the dentate gyrus. J Neuroimmunol 37 787. PMID: 22030710.

Vivar et al (2012) Mixed electrical-chemical transmission between hippocampal mossy fibers and pyramidal cells. Eur J Neurosci 35 76. PMID: 22151275.

Abe et al (2011) The Etv1/Er81 transcription factor orchestrates activity-dependent gene regulation in the terminal maturation program of cerebellar granule cells. Neuroscience 108 12497. PMID: 21746923.

Bartoletti and Thoreson (2011) Quantal amplitude at the cone ribbon synapse can be adjusted by changes in cytosolic glutamate. Mol Vis 17 920. PMID: 21541265.

Biase et al (2011) NMDA receptor signaling in oligodendrocyte progenitors is not required for oligodendrogenesis and myelination. J Neurophysiol 31 12650. PMID: 21880926.

Christie et al (2011) Ca(2+)-dependent enhancement of release by subthreshold somatic depolarization. Nat Neurosci 14 62. PMID: 21170054.

Chu et al (2011) Synaptic responses evoked by tactile stimuli in Purkinje cells in mouse cerebellar cortex Crus II in vivo. PLoS One 6 e22752. PMID: 21818384.

Crawford et al (2011) Calcium-independent inhibitory G-protein signaling induces persistent presynaptic muting of hippocampal synapses. Proc Natl Acad Sci U S A 31 979. PMID: 21248122.

Etherton et al (2011) An autism-associated point mutation in the neuroligin cytoplasmic tail selectively impairs AMPA receptor-mediated synaptic transmission in hippocampus. EMBO J 30 2908. PMID: 21642956.

Higley et al (2011) Cholinergic interneurons mediate fast VGluT3-dependent glutamatergic transmission in the striatum. PLoS One 6 e19155. PMID: 21544206.

Holderith et al (2011) Cannabinoids attenuate hippocampal γ oscillations by suppressing excitatory synaptic input onto CA3 pyramidal neurons and fast spiking basket cells. Eur J Neurosci 589 4921. PMID: 21859823.

Kopach et al (2011) Inflammation alters trafficking of extrasynaptic AMPA receptors in tonically firing lamina II neurons of the rat spinal dorsal horn. Pain 152 912. PMID: 21282008.

Straub et al (2011) Distinct functions of kainate receptors in the brain are determined by the auxiliary subunit Neto1. Nat Neurosci 14 866. PMID: 21623363.

Uschakov et al (2011) Sleep-deprivation regulates α-2 adrenergic responses of rat hypocretin/orexin neurons. PLoS One 6 e16672. PMID: 21347440.

Zhang et al (2011) Developmental maturation of excitation and inhibition balance in principal neurons across four layers of somatosensory cortex. J Neurosci 174 45931. PMID: 21115101.

Zhang and Sun (2011) Development of NMDA NR2 subunits and their roles in critical period maturation of neocortical GABAergic interneurons. Neuropsychopharmacology 71 221. PMID: 20936660.

Biase et al (2010) Excitability and synaptic communication within the oligodendrocyte lineage. J Neurosci 30 3600. PMID: 20219994.

Bissonnette et al (2010) Effect of hypoxia on expiratory muscle activity in fetal sheep. Respir Physiol Neurobiol 171 110. PMID: 20215050.

Buchanan et al (2010) Facilitation of long-term potentiation by muscarinic M(1) receptors is mediated by inhibition of SK channels. Neuron 68 948. PMID: 21145007.

Cao and Tsien (2010) Different relationship of N- and P/Q-type Ca2+ channels to channel-interacting slots in controlling neurotransmission at cultured hippocampal synapses. J Neurosci 30 4536. PMID: 20357104.

Chang et al (2010) Rapid activation of dormant presynaptic terminals by phorbol esters. J Neurosci 30 10048. PMID: 20668189.

Higley and Sabatini (2010) Competitive regulation of synaptic Ca2+ influx by D2 dopamine and A2A adenosine receptors. Nat Neurosci 13 958. PMID: 20601948.

Hossaini et al (2010) Nociceptive stimulation induces expression of Arc/Arg3.1 in the spinal cord with a preference for neurons containing enkephalin. Proc Natl Acad Sci U S A 6 43. PMID: 20653942.

Jackson et al (2010) Control of cerebellar long-term potentiation by P-Rex-family guanine-nucleotide exchange factors and phosphoinositide 3-kinase. PLoS One 5 e11962. PMID: 20694145.

Lobb et al (2010) A dynamic role for GABA receptors on the firing pattern of midbrain dopaminergic neurons. J Neurophysiol 104 403. PMID: 20445035.

Mah et al (2010) Selected SALM (synaptic adhesion-like molecule) family proteins regulate synapse formation. J Physiol 30 5559. PMID: 20410109.

Mapelli et al (2010) High-Pass Filtering and Dynamic Gain Regulation Enhance Vertical Bursts Transmission along the Mossy Fiber Pathway of Cerebellum. Proc Natl Acad Sci U S A 4 14. PMID: 20577586.

Mapelli et al (2010) Combinatorial responses controlled by synaptic inhibition in the cerebellum granular layer. Neuropharmacology 103 250. PMID: 19906881.

Peng et al (2010) Postsynaptic spiking homeostatically induces cell-autonomous regulation of inhibitory inputs via retrograde signaling. J Neurosci 30 16220. PMID: 21123568.

Potier et al (2010) Contribution of the d-Serine-Dependent Pathway to the Cellular Mechanisms Underlying Cognitive Aging. Front Aging Neurosci 2 1. PMID: 20552041.

Cho et al (2009) Chronic CXCL10 alters neuronal properties in rat hippocampal culture. J Neurosci 207 92. PMID: 19167097.

Citri et al (2009) N-methyl-D-aspartate receptor- and metabotropic glutamate receptor-dependent long-term depression are differentially regulated by the ubiquitin-proteasome system. J Neurophysiol 30 1443. PMID: 19821836.

Jiang et al (2009) AMPA receptor trafficking and synaptic plasticity require SQSTM1/p62. Hippocampus 19 392. PMID: 19004011.

Kenny et al (2009) NMDA receptors regulate nicotine-enhanced brain reward function and intravenous nicotine self-administration: role of the ventral tegmental area and central nucleus of the amygdala. Neuropsychopharmacology 34 266. PMID: 18418357.

Lin et al (2009) Characterization of engineered channelrhodopsin variants with improved properties and kinetics. Biophys J 96 1803. PMID: 19254539.

Sun (2009) Experience-dependent intrinsic plasticity in interneurons of barrel cortex layer IV. J Neurosci 102 2955. PMID: 19741102.

Tottene et al (2009) Enhanced excitatory transmission at cortical synapses as the basis for facilitated spreading depression in Ca(v)2.1 knockin migraine mice. Neuron 61 762. PMID: 19285472.

Varela et al (2009) D1/D5 modulation of synaptic NMDA receptor currents. J Neurosci 29 3109. PMID: 19279248.

Yu et al (2009) Specific synapses develop preferentially among sister excitatory neurons in the neocortex. EMBO Rep 458 501. PMID: 19204731.

Baltan et al (2008) White matter vulnerability to ischemic injury increases with age because of enhanced excitotoxicity. J Neurosci 28 1479. PMID: 18256269.

Cho and Gruol (2008) The chemokine CCL2 activates p38 mitogen-activated protein kinase pathway in cultured rat hippocampal cells. J Neurosci 199 94. PMID: 18584881.

Giordano et al (2008) Apoptosis induced by domoic acid in mouse cerebellar granule neurons involves activation of p38 and JNK MAP kinases. J Physiol 52 1100. PMID: 18164102.

Gould et al (2008) Involvement of AMPA receptors in the antidepressant-like effects of lithium in the mouse tail suspension test and forced swim test. Neuropharmacology 54 577. PMID: 18096191.

Iwasato et al (2008) Cortical adenylyl cyclase 1 is required for thalamocortical synapse maturation and aspects of layer IV barrel development. J Neurosci 28 5931. PMID: 18524897.

Karson et al (2008) Cholecystokinin inhibits endocannabinoid-sensitive hippocampal IPSPs and stimulates others. J Biol Chem 54 117. PMID: 17689570.

Kim and Tsien (2008) Synapse-specific adaptations to inactivity in hippocampal circuits achieve homeostatic gain control while dampening network reverberation. Neuron 58 925. PMID: 18579082.

Maher and Westbrook (2008) Co-transmission of dopamine and GABA in periglomerular cells. J Neurophysiol 99 1559. PMID: 18216231.

Romo-Parra et al (2008) GABA actions in hippocampal area CA3 during postnatal development: differential shift from depolarizing to hyperpolarizing in somatic and dendritic compartments. J Neurosci 99 1523. PMID: 18216229.

Shin et al (2008) Dendritic glutamate release produces autocrine activation of mGluR1 in cerebellar Purkinje cells. Nature 105 746. PMID: 18174329.

Albright et al (2007) Increased thalamocortical synaptic response and decreased layer IV innervation in GAP-43 knockout mice. J Neurophysiol 98 1610. PMID: 17581849.

Empson et al (2007) Plasma membrane Ca2+ ATPase 2 contributes to short-term synapse plasticity at the parallel fiber to Purkinje neuron synapse. Proc Natl Acad Sci U S A 27 3753. PMID: 17409239.

Fukunaga et al (2007) Potent and specific action of the mGlu1 antagonists YM-298198 and JNJ16259685 on synaptic transmission in rat cerebellar slices. Br J Pharmacol 151 870. PMID: 17502847.

Gustafson et al (2007) Endogenous D-serine contributes to NMDA-receptor-mediated light-evoked responses in the vertebrate retina. J Neurophysiol 98 122. PMID: 17507508.

Jan and Westbrook (2007) Disynaptic amplification of metabotropic glutamate receptor 1 responses in the olfactory bulb. J Neurosci 27 132. PMID: 17202480.

Jensen et al (2007) Presynaptic plasma membrane Ca2+ ATPase isoform 2a regulates excitatory synaptic transmission in rat hippocampal CA3. Chem Senses 579 85. PMID: 17170045.

Li et al (2007) Axon and dendrite geography predict the specificity of synaptic connections in a functioning spinal cord network. Neural Dev 2 17. PMID: 17845723.

Limon et al (2007) Properties of GluR3 receptors tagged with GFP at the amino or carboxyl terminus. Proc Natl Acad Sci U S A 104 15526. PMID: 17881566.

Young and Sun (2007) Long-term modifications in the strength of excitatory associative inputs in the piriform cortex. Proc Natl Acad Sci U S A 32 783. PMID: 17634388.

Ziskin et al (2007) Vesicular release of glutamate from unmyelinated axons in white matter. Front Integr Neurosci 10 321. PMID: 17293857.

Bäckström and Hyytiä (2006) Ionotropic and metabotropic glutamate receptor antagonism attenuates cue-induced cocaine seeking. Neuropsychopharmacology 31 778. PMID: 16123768.

Jakubs et al (2006) Environment matters: synaptic properties of neurons born in the epileptic adult brain develop to reduce excitability. Neuron 52 1047. PMID: 17178407.

Surges et al (2006) Regulated expression of HCN channels and cAMP levels shape the properties of the h current in developing rat hippocampus. Mol Pain 24 94. PMID: 16882011.

Takayasu et al (2006) Glial glutamate transporters maintain one-to-one relationship at the climbing fiber-Purkinje cell synapse by preventing glutamate spillover. J Neurosci 26 6563. PMID: 16775144.

Calò et al (2005) Interactions between ephrin-B and metabotropic glutamate 1 receptors in brain tissue and cultured neurons. J Neurosci 25 2245. PMID: 15745950.

Gómez-Lira et al (2005) Programmed and induced phenotype of the hippocampal granule cells. J Neurosci 25 6939. PMID: 16049169.

Newman (2005) Calcium increases in retinal glial cells evoked by light-induced neuronal activity. Nat Methods 25 5502. PMID: 15944378.

Rhee et al (2005) Augmenting neurotransmitter release by enhancing the apparent Ca2+ affinity of synaptotagmin 1. J Neurosci 102 18664. PMID: 16352718.

Sims and Hartell (2005) Differences in transmission properties and susceptibility to long-term depression reveal functional specialization of ascending axon and parallel fiber synapses to Purkinje cells. EMBO Rep 25 3246. PMID: 15788782.

Weitlauf et al (2005) Activation of NR2A-containing NMDA receptors is not obligatory for NMDA receptor-dependent long-term potentiation. Neurochem Int 25 8386. PMID: 16162920.

Chevaleyre and Castillo (2004) Endocannabinoid-mediated metaplasticity in the hippocampus. Neuron 43 871. PMID: 15363397.

Cronberg et al (2004) Glucose but not lactate in combination with acidosis aggravates ischemic neuronal death in vitro. Proc Natl Acad Sci U S A 35 753. PMID: 14963271.

Huang et al (2004) Astrocyte glutamate transporters regulate metabotropic glutamate receptor-mediated excitation of hippocampal interneurons. J Neurosci 24 4551. PMID: 15140926.

Tongiorgi et al (2004) Brain-derived neurotrophic factor mRNA and protein are targeted to discrete dendritic laminas by events that trigger epileptogenesis. Development 24 6842. PMID: 15282290.

Fu et al (2003) Functional excitatory synapses in HEK293 cells expressing neuroligin and glutamate receptors. J Neurophysiol 90 3950. PMID: 12930820.

Paladini et al (2003) Dopamine controls the firing pattern of dopamine neurons via a network feedback mechanism. Proc Natl Acad Sci U S A 100 2866. PMID: 12604788.

Andrieux et al (2002) The suppression of brain cold-stable microtubules in mice induces synaptic defects associated with neuroleptic-sensitive behavioral disorders. Genes Dev 16 2350. PMID: 12231625.

Yamaguchi et al (2002) A GDP/GTP exchange protein for the Rab3 small G protein family up-regulates a postdocking step of synaptic exocytosis in central synapses. J Neurophysiol 99 14536. PMID: 12388783.

Rzeski et al (2001) Glutamate antagonists limit tumor growth. Proc Natl Acad Sci U S A 98 6372. PMID: 11331750.

Bell et al (2000) Histamine depolarizes cholinergic interneurones in the rat striatum via a H(1)-receptor mediated action. Br J Pharmacol 131 1135. PMID: 11082121.

Bureau et al (2000) Kainate receptor-mediated synaptic currents in cerebellar Golgi cells are not shaped by diffusion of glutamate. Proc Natl Acad Sci U S A 97 6838. PMID: 10841579.

Casado et al (2000) Presynaptic N-methyl-D-aspartate receptors at the parallel fiber-Purkinje cell synapse. J Neurosci 97 11593. PMID: 11016958.

Koester and Sakmann (1998) Calcium dynamics in single spines during coincident pre- and postsynaptic activity depend on relative timing of back-propagating action potentials and subthreshold excitatory postsynaptic potentials. PLoS One 95 9596. PMID: 9689126.

Miettinen et al (1997) Spreading depression and focal brain ischemia induce cyclooxygenase-2 in cortical neurons through N-methyl-D-aspartic acid-receptors and phospholipase A2. J Psychopharmacol 94 6500. PMID: 9177247.

Tabor and Friedrich Pharmacological analysis of ionotropic glutamate receptor function in neuronal circuits of the zebrafish olfactory bulb. PLoS One 3 e1416. PMID: 18183297.

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