NAN-190 hydrobromide

Cat. No. 0553

NAN-190 hydrobromide C23H27N3O3.HBr [115338-32-4]

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Chemical Name: 1-(2-Methoxyphenyl)-4-(4-phthalimidobutyl)piperazine hydrobromide

Biological Activity

5-HT1A antagonist.

Technical Data

M.Wt:
474.4
Formula:
C23H27N3O3.HBr
Solubility:
Soluble to 10 mM in DMSO
Purity:
>98 %
Storage:
Store at RT
CAS No:
115338-32-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

Douris (1992) Effects of the putative 5-HT1A receptor antagonist NAN-190 on free feeding and on feeding induced by the 5-HT1A receptor agonist 8-OH-DPAT in the rat. Eur.J.Pharmacol. 219 105. PMID: 1397037.

Glennon et al (1988) Arylpiperazine derivatives as high affinity 5-HT1A serotonin ligands. J.Med.Chem. 31 1968. PMID: 3172131.

Williams and Glennon (1988) NAN-190: an arylpiperazine analog that antagonizes the stimulus effects of the 5-HT1A agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT). Eur.J.Pharmacol. 154 339. PMID: 2976673.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for NAN-190 hydrobromide include:

Demarque and (2010) Activity-dependent expression of Lmx1b regulates specification of serotonergic neurons modulating swimming behavior. Neuron 67 321. PMID: 20670838.

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Keywords: NAN-190 hydrobromide, supplier, 5-HT1A, antagonists, Serotonin, Receptors, 5-HT1, NAN190, Tocris Bioscience, 5-HT1A Receptor Antagonist products

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