Naltriben mesylate

Cat. No. 0892

Naltriben mesylate C26H25NO4.CH3SO3H [122517-78-6]

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Chemical Name: 17-(Cyclopropylmethyl)-6,7-didehydro-3,14β-dihydroxy-4,5α-epoxy-6,7-2',3'-benzo[b]furanomorphinan mesylate

Biological Activity

Selective and potent δ-opioid receptor antagonist (Ki values are 0.013, 19 and 152 nM for δ, μ and κ receptors respectively). Displays selectivity for the δ2 subtype in vivo.

Licensing Information

Sold with the permission of the University of Minnesota

Technical Data

M.Wt:
511.59
Formula:
C26H25NO4.CH3SO3H
Solubility:
Soluble to 50 mM in DMSO with gentle warming
Storage:
Desiccate at RT
CAS No:
122517-78-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Thorat and Hammond (1997) Modulation of nociception by microinjection of delta-1 and delta-2 opioid receptor ligands in the ventromedial medulla of the rat. J.Pharmacol.Exp.Ther. 283 1185. PMID: 9399992.

Miyamoto et al (1993) Involvement of delta2 opioid receptors in the development of morphine dependence in mice. J.Pharmacol.Exp.Ther. 264 1141. PMID: 8383738.

Portoghese et al (1991) Role of spacer and address components in peptidomimetic δ opioid receptor antagonists related to naltrindole. J.Med.Chem. 34 1715. PMID: 1851846.

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Keywords: Naltriben mesylate, supplier, δ2-opioid, delta2-opioid, selective, antagonists, DOP, Receptors, OP1, Tocris Bioscience, δ Opioid Receptor Antagonist products

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