Cat. No. 0677
Chemical Name: (5α)-17-(Cyclopropylmethyl)-4,5-epox
Biological ActivityOpioid antagonist.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Gold et al (1982) Naltrexone, opiate addiction, and endorphins. Med.Res.Rev. 2 211. PMID: 6289026.
Tempel et al (1982) Supersensitivity of brain opiate receptor subtypes after chronic naltrexone treatment. Life Sci. 31 1401. PMID: 6292636.
Zukin et al (1982) Naltrexone-induced opiate receptor supersensitivity. Brain Res. 245 285. PMID: 6289965.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products. Selected citations for Naltrexone hydrochloride include:
Leskelä et al (2012) Cys-27 variant of human δ-opioid receptor modulates maturation and cell surface delivery of Phe-27 variant via heteromerization. J Biol Chem 287 5008. PMID: 22184124.
Jones et al (2010) Identification of a κ-opioid agonist as a potent and selective lead for drug development against human African trypanosomiasis. Biochem Pharmacol 80 1478. PMID: 20696141.
Markkanen and Petäjä-Repo (2008) N-glycan-mediated quality control in the endoplasmic reticulum is required for the expression of correctly folded delta-opioid receptors at the cell surface. J Biol Chem 283 29086. PMID: 18703511.
Do you know of a great paper that uses Naltrexone hydrochloride from Tocris? If so please let us know.
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Keywords: Naltrexone hydrochloride, supplier, Broad, spectrum, antagonists, Opioids, Receptors, Tocris Bioscience, Miscellaneous Opioid Antagonist products
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