Naloxonazine dihydrochloride

Cat. No. 0591

Naloxonazine dihydrochloride C38H42N4O6.2HCl [880759-65-9]

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Chemical Name: Bis-[5-α-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl)-morphinan-6-ylidene] hydrazine dihydrochloride

Biological Activity

Potent opioid antagonist, selective for μ1 receptors.

Technical Data

M.Wt:
723.69
Formula:
C38H42N4O6.2HCl
Solubility:
Soluble to 25 mM in water
Purity:
>98 %
Storage:
Store at RT
CAS No:
880759-65-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

Paul et al (1988) Differential blockade by naloxonazine of two μ opiate actions: analgesic and inhibition of gastrointestinal transit. Eur.J.Pharmacol. 149 403. PMID: 2842168.

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Citations are publications that use Tocris products. Selected citations for Naloxonazine dihydrochloride include:

Gerhold et al (2015) Pronociceptive and Antinociceptive Effects of Buprenorphine in the Spinal Cord Dorsal Horn Cover a Dose Range of Four Orders of Magnitude. J Neurosci 35 9580. PMID: 26134641.

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Keywords: Naloxonazine dihydrochloride, supplier, Selective, antagonists, μ-opioid, mu-opioid, μ1-opioid, mu1-opioid, MOP, Receptors, OP3, Tocris Bioscience, μ Opioid Receptor Antagonist products

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