Cat. No. 0591
Chemical Name: Bis-[5-α-4,5-Epoxy-3,14-dihydroxy-17
Biological ActivityPotent opioid antagonist, selective for μ1 receptors.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Paul et al (1988) Differential blockade by naloxonazine of two μ opiate actions: analgesic and inhibition of gastrointestinal transit. Eur.J.Pharmacol. 149 403. PMID: 2842168.
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Citations are publications that use Tocris products. Selected citations for Naloxonazine dihydrochloride include:
Gerhold et al (2015) Pronociceptive and Antinociceptive Effects of Buprenorphine in the Spinal Cord Dorsal Horn Cover a Dose Range of Four Orders of Magnitude. J Neurosci 35 9580. PMID: 26134641.
Yi et al (2015) Low-frequency electroacupuncture suppresses focal epilepsy and improves epilepsy-induced sleep disruptions. BMC Cell Biol 22 49. PMID: 26150021.
Lee et al (2012) Prostatic relaxation induced by loperamide is reduced in spontaneously hypertensive rats. J Biomed Sci 2012 941685. PMID: 22645476.
Do you know of a great paper that uses Naloxonazine dihydrochloride from Tocris? If so please let us know.
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Keywords: Naloxonazine dihydrochloride, supplier, Selective, antagonists, μ-opioid, mu-opioid, μ1-opioid, mu1-opioid, MOP, Receptors, OP3, Tocris Bioscience, μ Opioid Receptor Antagonist products
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