Naftopidil hydrochloride

Cat. No. 0597

Naftopidil hydrochloride C24H28N2O3.HCl [1164469-60-6]

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Chemical Name: 4-(2-Methoxyphenyl)-α-[(1-naphthalenyloxy)methyl]-1-piperazineethanol hydrochloride

Biological Activity

An α1-adrenoceptor antagonist with only weak antagonism at post-junctional α2 receptors; a potent, persistent antihypertensive and vasodilator.

Technical Data

M.Wt:
428.96
Formula:
C24H28N2O3.HCl
Solubility:
Soluble to 100 mM in DMSO
Purity:
>98 %
Storage:
Store at RT
CAS No:
1164469-60-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Muramatsu et al (1991) Pharmacological profile of the novel alpha-adrenoceptor antagonist KT-611 (naftopidil). Jpn.J.Pharmacol. 55 391. PMID: 1677438.

Borbe and Peter (1990) Alpha-1-adrenoceptor-binding material in rat plasma following single oral administration of naftopidil. Arzneimittelforschung 40 253. PMID: 1971750.

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Keywords: Naftopidil hydrochloride, supplier, α1-adrenoceptor, alpha1-adrenoceptor, a1-adrenoceptor, antagonists, α1-adrenergic, alpha1-adrenergic, a1-adrenergic, Receptors, Tocris Bioscience, Adrenergic α1 Receptor Antagonist products

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