Cat. No. 0432

 C20H14ClN3 [78351-75-4]

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Chemical Name: 1-(3-Chlorophenylamino)-4-phenylphthalazine

Biological Activity

Specific inhibitor of cyclic GMP phosphodiesterase, selective for PDE5 (IC50 = 0.5 μM).

Technical Data

Soluble to 50 mM in DMSO and to 5 mM in ethanol
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Hagiwara et al (1984) Effect of 1-(3-chloroanilino)-4-phenylphthalazine (MY-5445), a specific inhibitor of cyclic GMP phosphodiesterase, on human platelet aggregation. J.Pharmacol.Exp.Ther. 228 467. PMID: 6141286.

Hidaka and Endo et al (1984) Selective inhibitors of three forms of cyclic nucleotide phosphodiesterase, basic and potential clinical applications. Adv.Cyclic Nucleotide Protein Phosphorylation Res. 16 245. PMID: 6144253.

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Keywords: MY-5445, supplier, PDE5, inhibitors, inhibits, PDE, Phosphodiesterases, MY, 5445, Tocris Bioscience, Phosphodiesterase Inhibitor products

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