Cat. No. 0432
Chemical Name: 1-(3-Chlorophenylamino)-4-phenylpht
Biological ActivitySpecific inhibitor of cyclic GMP phosphodiesterase, selective for PDE5 (IC50 = 0.5 μM).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Hagiwara et al (1984) Effect of 1-(3-chloroanilino)-4-phenylphthalazine (MY-5445), a specific inhibitor of cyclic GMP phosphodiesterase, on human platelet aggregation. J.Pharmacol.Exp.Ther. 228 467. PMID: 6141286.
Hidaka and Endo et al (1984) Selective inhibitors of three forms of cyclic nucleotide phosphodiesterase, basic and potential clinical applications. Adv.Cyclic Nucleotide Protein Phosphorylation Res. 16 245. PMID: 6144253.
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Citations are publications that use Tocris products.
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Keywords: MY-5445, supplier, PDE5, inhibitors, inhibits, PDE, Phosphodiesterases, MY, 5445, Tocris Bioscience, Phosphodiesterase Inhibitor products
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