Cat. No. 0583

Minoxidil C9H15N5O [38304-91-5]

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Chemical Name: 6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide

Biological Activity

Antihypertensive. Antialopecia agent. Kir6 channel (KATP) activator.

Technical Data

Soluble to 25 mM in ethanol and to 25 mM in DMSO with gentle warming
>99 %
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Lachgar et al (1998) Minoxidil upregulates the expression of vascular endothelial growth factor in human hair dermal papilla cells. Br.J.Dermatol. 138 407. PMID: 9580790.

Meisheri et al (1993) Enzymatic and non-enzymatic sulfation mechanisms in the biological actions of minoxidil. Biochem.Pharmacol. 45 271. PMID: 8435087.

Tsoporis et al (1993) Effects of the arterial vasodilator minoxidil on cardiovascular structure and sympathetic activity in spontaneously hypertensive rats. J.Hypertens. 11 1337. PMID: 8133016.

Merck Index 12 6290.

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Citations are publications that use Tocris products.

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Keywords: Minoxidil, supplier, K+, channel, KATP, openers, Potassium, KIR, Channels, Inward, Rectifier, antihypertensive, activators, Kir6, Tocris Bioscience, Inward Rectifier Potassium (Kir) Channel Activator products

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