Benazepril hydrochloride

Cat. No. 2578

Benazepril hydrochloride C24H28N2O5.HCl [86541-74-4]

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Alternative Name: CGS 14824A

Chemical Name: (3S)-3-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid hydrochloride

Biological Activity

Non-peptide angiotensin-converting enzyme (ACE) inhibitor. Reduces blood pressure and myocardial hypertrophy in spontaneous hypertensive rats.

Technical Data

M.Wt:
460.96
Formula:
C24H28N2O5.HCl
Solubility:
Soluble to 50 mM in water and to 100 mM in DMSO
Purity:
>99 %
Storage:
Desiccate at +4°C
CAS No:
86541-74-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Ishibashi et al (1991) Hemodynamic effects of benazepril, an angiotensin-converting enzyme inhibitor, as studied in conscious normotensive dogs. Cardiovas.Drugs Ther. 5 635.

Takemori et al (1991) Effect of benazepril hydrochloride on cardiac hypertrophy in spontaneous hypertensive rats. Arzneim.-Forsch. 41 612.

Yamamoto et al (1991) General pharmacology of the novel angiotensin converting enzyme inhibitor benazepril hydrochloride. Effects on cardiovascular, visceral and renal functions and on hemodynamics. Arzneim.-Forsch. 41 913.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for Benazepril hydrochloride include:

Bulavina et al (2013) NTPDase1 activity attenuates microglial phagocytosis. Purinergic Signal 9 199. PMID: 23208703.

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Keywords: Benazepril hydrochloride, supplier, Angiotensin-converting, enzyme, ACE, inhibitors, inhibits, Proteinases, Proteases, CGS14824A, Tocris Bioscience, Angiotensin-Converting Enzyme Inhibitor products

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