MOG (35-55)

Cat. No. 2568

MOG (35-55) Met-Glu-Val-Gly-Trp-Tyr-Arg-Ser-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-Lys

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Biological Activity

Myelin oligodendrocyte glycoprotein (MOG) 35-55 is a minor component of CNS myelin. Produces a relapsing-remitting neurological disease with extensive plaque-like demyelination, common to the manifestations of multiple sclerosis. Induces strong T and B cell responses and is highly encephalitogenic.

Technical Data

M.Wt:
2581.97
Formula:
C118H177N35O29S
Sequence:
MEVGWYRSPFSRVVHLYRNGK
Solubility:
Soluble to 0.50 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
149635-73-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Zhang et al (2004) T cell and antibody responses in remitting-relapsing experimental autoimmune encephalomyelitis in (C57BL/6xSJL) F1 mice. J.Neuroimmunol. 148 1. PMID: 14975581.

Slavin et al (1998) Induction of a multiple sclerosis-like disease in mice with an immunodominant epitope of myelin oligodendrocyte glycoprotein. Autoimmunity 28 109. PMID: 9771980.

Ichikawa et al (1996) Analysis of the fine B cell specificity during the chronic/relapsing course of a multiple sclerosis-like disease in Lewis rats injected with the encephalitogenic myelin oligodendrocyte glycoprotein peptide 35-55. J.Immunol. 157 919. PMID: 8752946.

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Keywords: MOG (35-55), supplier, Encephalitogenic, myelin, oligodendrocyte, glycoprotein, fragment, Neuronal, Metabolism, Tocris Bioscience, Neuronal Metabolism products

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