Cat. No. 2565
Chemical Name: 2-[2-[4-[(3-phenoxyphenyl)methyl]-1
Biological ActivitySelective, non-peptide CCR8 chemokine receptor agonist (IC50 values are 1.8 and 2.6 μM for human and mouse receptors respectively). Displays no activity at CCR4, CXCR3, CXCR4 and CCR5 and shows > 28-fold selectivity over 26 other GPCRs (less selective at α2A and 5-HT receptors). Induces chemotaxis and inhibits Env-mediated (HIV) cell-cell fusion.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Haskell et al (2006) Identification and characterization of a potent, selective nonpeptide agonist of the CC chemokine receptor CCR8. Mol.Pharmacol. 69 309. PMID: 16221874.
If you know of a relevant reference for ZK 756326 please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses ZK 756326 from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: ZK 756326, supplier, Selective, non-peptide, CCR8, agonists, CXCR, Chemokine, Receptors, ZK756326, Tocris Bioscience, Chemokine CC Receptor Agonist products
Find multiple products by catalog number
New Products in this Area
Follow Tocris on LinkedIn
Visit our LinkedIn page for the latest Tocris news, events and updates.