α-Methyl-5-hydroxytryptamine maleate

Cat. No. 0557

a-Methyl-5-hydroxytryptamine maleate C11H14N2O.C4H4O4 [97469-12-0]

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Biological Activity

5-HT2B receptor selective agonist with pKi values of 8.4, 6.1 and 7.3 at 5-HT2B, 5-HT2A and 5-HT2C receptors respectively.

Technical Data

M.Wt:
306.32
Formula:
C11H14N2O.C4H4O4
Solubility:
Soluble to 10 mM in water and to 100 mM in DMSO
Purity:
>98 %
Storage:
Store at -20°C
CAS No:
97469-12-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Certificate of Analysis / Product Datasheet
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Baxter et al (1995) 5-HT2 receptor subtypes: a family re-united? TiPS 16 105. PMID: 7792930.

Wilson et al (1990) 5-Hydroxytryptamine3 receptors mediate tachycardia in conscious instrumented dogs. J.Pharmacol.Exp.Ther. 252 683. PMID: 1968974.

Richardson et al (1985) Identification of serotonin M-receptor sub-types and their specific blockade by a new class of drugs. Nature 316 126. PMID: 3839291.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for α-Methyl-5-hydroxytryptamine maleate include:

Coulon et al (2011) Activity Modes in Thalamocortical Relay Neurons are Modulated by G(q)/G(11) Family G-proteins - Serotonergic and Glutamatergic Signaling. Front Cell Neurosci 4 132. PMID: 21267426.

Do you know of a great paper that uses α-Methyl-5-hydroxytryptamine maleate from Tocris? If so please let us know.

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