CD 1530

Cat. No. 2554

CD 1530 C27H26O3 [107430-66-0]

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Chemical Name: 4-(6-Hydroxy-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)benzoic acid

Biological Activity

Potent and selective RARγ receptor agonist (Ki values are 150, 1500 and 2750 nM for RARγ, RARβ and RARα receptors respectively). Activates transcriptional activity (AC50 = 1.8 nM).

Technical Data

M.Wt:
398.49
Formula:
C27H26O3
Solubility:
Soluble to 100 mM in DMSO
Purity:
>98 %
Storage:
Store at +4°C
CAS No:
107430-66-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Thacher et al (2000) Therapeutic applications for ligands of retinoid receptors. Curr.Pharmaceut.Des. 6 25.

If you know of a relevant reference for CD 1530 please let us know.

Citations are publications that use Tocris products. Selected citations for CD 1530 include:

Duprey-Díaz et al (2016) Exogenous Modulation of Retinoic Acid Signaling Affects Adult RGC Survival in the Frog Visual System afterOptic Nerve Injury PLoS One 11 e0162626. PMID: 27611191.

Garnaas et al (2012) Rargb regulates organ laterality in a zebrafish model of right atrial isomerism. Dev Biol 372 178. PMID: 22982668.

Do you know of a great paper that uses CD 1530 from Tocris? If so please let us know.

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Keywords: CD 1530, supplier, Potent, selective, RARγ, RARgamma, agonists, RAMBA, Retinoic, Acid, Receptors, CD1530, Tocris Bioscience, Retinoic Acid Receptor Agonist products

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