CD 1530

Cat. No. 2554

CD 1530 C27H26O3 [107430-66-0]

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Chemical Name: 4-(6-Hydroxy-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)benzoic acid

Biological Activity

Potent and selective RARγ receptor agonist (Ki values are 150, 1500 and 2750 nM for RARγ, RARβ and RARα receptors respectively). Activates transcriptional activity (AC50 = 1.8 nM).

Technical Data

M.Wt:
398.49
Formula:
C27H26O3
Solubility:
Soluble to 50 mM in 1eq. NaOH
Purity:
>98 %
Storage:
Store at +4°C
CAS No:
107430-66-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Thacher et al (2000) Therapeutic applications for ligands of retinoid receptors. Curr.Pharmaceut.Des. 6 25.

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Citations are publications that use Tocris products. Selected citations for CD 1530 include:

Garnaas et al (2012) Rargb regulates organ laterality in a zebrafish model of right atrial isomerism. Dev Biol 372 178. PMID: 22982668.

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Keywords: CD 1530, supplier, Potent, selective, RARγ, RARgamma, agonists, RAMBA, Retinoic, Acid, Receptors, CD1530, Tocris Bioscience, Retinoic Acid Receptor Agonist products

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