Cat. No. 0549
Alternative Name: Methylergonovine maleate
Chemical Name: [8β(S)]-9,10-Didehydro-N-[1-(hydroxy
Biological ActivityActive metabolite of methysergide (Cat. No. 1064); uterotonic agent and oxytocic.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Pertz (1993) 5-Hydroxytryptamine (5-HT) contracts the guinea-pig isolated iliac artery via 5-HT1-like and 5-HT2 receptors. Naunyn Schmiedebergs Arch.Pharmacol. 348 558. PMID: 8133899.
MacLennan and Martin (1990) Actions of non-peptide ergot alkaloids at 5-HT1-like and 5-HT2 receptors mediating vascular smooth muscle contraction. Naunyn Schmiedebergs Arch.Pharmacol. 342 120. PMID: 2234096.
Muller-Schweinitzer and Tapparelli (1986) Methylergometrine, an active metabolite of methysergide. Cephalalgia 6 35. PMID: 3698092.
Merck Index 12 6147.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products. Selected citations for Methylergometrine maleate include:
Chan et al (2015) Ergot Alkaloids (Re)generate New Leads as Antiparasitics. Cell Signal 9 e0004063. PMID: 26367744.
Do you know of a great paper that uses Methylergometrine maleate from Tocris? If so please let us know.
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Keywords: Methylergometrine maleate, supplier, Active, metabolite, methysergide, Serotonin, 5-HT-, 5-Hydroxytryptamine, Receptors, 5-HT, 5-HT1, 5-HT2, antagonists, Tocris Bioscience, Non-selective 5-HT products
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April 10 - 13, 2017