Methylergometrine maleate

Cat. No. 0549

Methylergometrine maleate C20H25N3O2.C4H4O4 [57432-61-8]

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Alternative Name: Methylergonovine maleate

Chemical Name: [8β(S)]-9,10-Didehydro-N-[1-(hydroxymethyl)propyl]-6-methylergoline-8-carboxamide maleate

Biological Activity

Active metabolite of methysergide (Cat. No. 1064); uterotonic agent and oxytocic.

Technical Data

Soluble to 25 mM in water
>98 %
Desiccate at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Pertz (1993) 5-Hydroxytryptamine (5-HT) contracts the guinea-pig isolated iliac artery via 5-HT1-like and 5-HT2 receptors. Naunyn Schmiedebergs Arch.Pharmacol. 348 558. PMID: 8133899.

MacLennan and Martin (1990) Actions of non-peptide ergot alkaloids at 5-HT1-like and 5-HT2 receptors mediating vascular smooth muscle contraction. Naunyn Schmiedebergs Arch.Pharmacol. 342 120. PMID: 2234096.

Muller-Schweinitzer and Tapparelli (1986) Methylergometrine, an active metabolite of methysergide. Cephalalgia 6 35. PMID: 3698092.

Merck Index 12 6147.

If you know of a relevant reference for Methylergometrine maleate please let us know.

Citations are publications that use Tocris products. Selected citations for Methylergometrine maleate include:

Chan et al (2015) Ergot Alkaloids (Re)generate New Leads as Antiparasitics. Cell Signal 9 e0004063. PMID: 26367744.

Do you know of a great paper that uses Methylergometrine maleate from Tocris? If so please let us know.

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Keywords: Methylergometrine maleate, supplier, Active, metabolite, methysergide, Serotonin, 5-HT-, 5-Hydroxytryptamine, Receptors, 5-HT, 5-HT1, 5-HT2, antagonists, Tocris Bioscience, Non-selective 5-HT products

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