Ochratoxin A

Cat. No. 1291

Ochratoxin A C20H18ClNO6 [303-47-9]

Price and Availability

For Ochratoxin A pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: N-[[(3R)-5-Chloro-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl]carbonyl]-L-phenylalanine

Biological Activity

Mycotoxin that increases activity of the endoplasmic reticulum ATP-dependent calcium pump. Induces JNK activation and apoptosis in MDCK-C7 cells at nanomolar concentrations. Stimulates lipid peroxidation.

Technical Data

M.Wt:
403.82
Formula:
C20H18ClNO6
Solubility:
Soluble to 50 mM in ethanol and to 100 mM in DMSO
Purity:
>99 %
Storage:
Desiccate at +4°C
CAS No:
303-47-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Select another batch:
Safety Data Sheet: View Safety Data Sheet

Gekle et al (2000) Ochratoxin A induces JNK activation and apoptosis in MDCK-C7 cells at nanomolar concentrations. J.Pharmacol.Exp.Ther. 293 837. PMID: 10869383.

Chong and Rahimtula (1992) Alterations in ATP-dependent calcium uptake by rat renal cortex microsomes following ochratoxin A administration in vitro. Biochem.Pharmacol. 44 1401. PMID: 1417961.

Dirheimer and Creppy (1991) Mechanism of action of ochratoxin A. IARC Sci.Publ. 115 171. PMID: 1820332.

Omar et al (1991) Role of cytochrome-P-450 in ochratoxin-A stimulated lipid-peroxidation. J.Biochem.Toxicol. 6 203. PMID: 1770504.

Merck Index 12 6836.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products.

Do you know of a great paper that uses Ochratoxin A from Tocris? If so please let us know.

View Related Products by Target

View Related Products by Product Action

Keywords: Ochratoxin A, supplier, Stimulates, stimulators, SERCA-ATPase, Ca2+, pump, activity, modulators, Ca2+-ATPase, Calcium-ATPase, Ion, Transporters, Pumps, OchratoxinA, Tocris Bioscience, Ca2+-ATPase Activator products

Quick Order

Find multiple products by catalog number

divider line

New Product Guide

New Product Guide (Spring/Summer 2016)

Our New Product guide highlights over 110 new products added in the first half of 2016. View PDF today.

divider line

New Products in this Area

CDN 1163

SERCA2 allosteric activator

Sign-up for new product e-alerts
divider line

Bio-Techne Events

IVBM 2016

IVBM 2016

October 30 - November 3, 2016

Boston, MA, USA

Booth: 2