Cat. No. 2538
Chemical Name: 3-(Methylamino)-L-alanine hydrochloride
Biological ActivityNeurotoxic glutamate agonist originally isolated from Cycas circinalis. Implicated in the pathogenesis of amyotrophic lateral sclerosis-Parkinsonism-dementia complex of Guam (Guam ALS-PD).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Weiss et al (1989) Neurotoxicity of β-N-methylamino-L-alanine (BMAA) and β-N-oxalylamino-L-alanine (BOAA) on cultured cortical neurons. Brain Res. 497 64. PMID: 2551452.
Vega et al (1968) The preparation of L- and D-α-amino-β<-methylaminopropionic acids and the identification of the compound isolated from Cycas circinalis as the L-isomer. Phytochemistry 7 1885.
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Keywords: L-BMAA hydrochloride, supplier, Neurotoxic, amino, acid, Glutamate, mGlur, Receptors, Metabotropic, iGluR, Ionotropic, Tocris Bioscience, Miscellaneous Glutamate products
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