Cat. No. 2521
Chemical Name: 5-Nitroso-8-quinolinol
Biological ActivityHistone deacetylase inhibitor. Causes cell differentiation and antiproliferative activity in MCF-7 human breast cancer cells in vitro and displays antitumor activity in vivo.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Martirosyan et al (2006) Actions of a histone deacetylase inhibitor NSC3852 (5-nitroso-8-quinolinol) link reactive oxygen species to cell differentiation and apoptosis in MCF-7 human mammary tumor cells. J.Pharmacol.Exp.Ther. 317 546. PMID: 16497787.
Martirosyan et al (2004) Differentiation-inducing quinolines as experimental breast cancer agents in the MCF-7 human breast cancer cell model. Biochem.Pharmacol. 68 1729. PMID: 15450938.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses NSC 3852 from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: NSC 3852, supplier, Histone, deacetylases, inhibitors, inhibits, HDAC, NSC3852, epigenetics, Tocris Bioscience, Histone Deacetylase Inhibitor products
Find multiple products by catalog number
New Products in this Area
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.