Cat. No. 2521
Chemical Name: 5-Nitroso-8-quinolinol
Biological ActivityHistone deacetylase inhibitor. Causes cell differentiation and antiproliferative activity in MCF-7 human breast cancer cells in vitro and displays antitumor activity in vivo.
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Martirosyan et al (2006) Actions of a histone deacetylase inhibitor NSC3852 (5-nitroso-8-quinolinol) link reactive oxygen species to cell differentiation and apoptosis in MCF-7 human mammary tumor cells. J.Pharmacol.Exp.Ther. 317 546. PMID: 16497787.
Martirosyan et al (2004) Differentiation-inducing quinolines as experimental breast cancer agents in the MCF-7 human breast cancer cell model. Biochem.Pharmacol. 68 1729. PMID: 15450938.
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Keywords: NSC 3852, supplier, Histone, deacetylases, inhibitors, inhibits, HDAC, NSC3852, epigenetics, Tocris Bioscience, Histone Deacetylase Inhibitor products