[Leu31,Pro34]-Neuropeptide Y (human, rat)
Cat. No. 1176
Alternative Name: [Leu31,Pro34]-NPY (human)
Biological ActivityHigh affinity neuropeptide Y Y1 receptor agonist (Ki = 0.39 nM). Also shows affinity for Y4 and Y5 receptors.
(Modifications: Tyr-36 = C-terminal amide)
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Kask et al (1998) Evidence for involvement of neuropeptide Y receptors in the regulation of food intake: studies with Y1-selective antagonist BIBP3226. Br.J.Pharmacol. 124 1507. PMID: 9723965.
Michel et al (1998) XVI.International Union of Pharmacology recommendations for the nomenclature of neuropeptide Y, peptide YY, and pancreatic polypeptide receptors. Pharmacol.Rev. 50 143. PMID: 9549761.
Bard et al (1995) Cloning and functional expression of a human Y4 subtype receptor for pancreatic polypeptide, neuropeptide Y, and peptide YY. J.Biol.Chem. 270 26762. PMID: 7592911.
Fuhlendorff et al (1990) [Leu31, Pro34]Neuropeptide Y: a specific Y1 receptor agonist. Proc.Natl.Acad.Sci.U.S.A. 87 182. PMID: 2153286.
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