Cat. No. 2492
Alternative Name: NSC 631156
Chemical Name: 4-Methyl-3-[(1-methyl-4-nitro-1H-im
Biological ActivityNovel, non-toxic immunosuppressive agent. Inhibits human mixed lymphocyte reaction in vitro (ED50 = 2.7 μM) and prolongs skin graft survival in mice. Produces a 98.1% reduction in antibody response following oral administration in rabbits.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Al-Safi et al (2003) Comparison of the effects of azathioprine and its novel non-mercaptopurine analog on antibody response in rabbits. Pol.J.Pharmacol. 55 239. PMID: 12926553.
Crawford et al (1996) Rational design of novel immunosuppressive drugs: analogues of azathioprine lacking the 6-mercaptopurine substituent retain or have enhanced immunosuppressive effects. J.Med.Chem. 39 2690. PMID: 8709098.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses MNITMT from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: MNITMT, supplier, Immunosuppressant, NSC631156, Tocris Bioscience, Immunosuppressant products
Find multiple products by catalog number
New Products in this Area
Antibiotic; selective apoptosis inducer of CLL cellsTrolox
Antioxidant vitamin E derivative
One Day Symposium
March 1, 2017
Amsterdam, The Netherlands