Cat. No. 2490
Alternative Name: Plavix
Chemical Name: Methyl 2-(4,5,6,7-tetrahydrothieno[3,2-c]p
Biological ActivitySelective, high affinity P2Y12 receptor antagonist (pKi = 6.9 for hP2Y12 receptor). Inhibits ADP-induced platelet aggregation; potent antithrombotic agent. Requires bioactivation, unlike PSB 0739 (Cat. No. 3983). (+)-Clopidogrel hydrogen sulfate (Cat. No. 1820) also available.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Kugelgen (2006) Pharmacological profiles of cloned mammalian P2Y-receptor subtypes. Pharmacol.Ther. 110 415. PMID: 16257449.
Savi and Herbert (2005) Clopidogrel and ticlopidine: P2Y12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis. Semin.Thromb.Haemostas. 31 174.
Savi et al (2001) P2Y12, a new platelet ADP receptor, target of clopidogrel. Biochem.Biophys.Res.Comm. 283 379.
If you know of a relevant reference for (±)-Clopidogrel hydrochloride please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses (±)-Clopidogrel hydrochloride from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: (±)-Clopidogrel hydrochloride, supplier, Selective, P2Y12, antagonists, Receptors, Purinergic, purinoceptors, p2yt, Tocris Bioscience, Purinergic (P2Y) Receptor Antagonist products
Find multiple products by catalog number
New Products in this Area
Highly potent P2Y12 antagonistFTY 720
Potent S1P receptor agonist; also immunosuppressantCinacalcet hydrochloride
Calcium-sensing receptor (CaSR) allosteric agonist; also CYP2D2 inhibitor and Ca2+ channel blocker; orally bioavailableAMG 837 hemicalcium salt
Potent free fatty acid receptor 1 (FFA1/GPR40) partial agonistUMB 68
GHB receptor ligandAZD 1283
High affinity P2Y12 antagonistEx 26
Potent and selective S1P1 receptor antagonist
June 14 - 17, 2017
Boston, MA, USA