(±)-Clopidogrel hydrochloride

Cat. No. 2490

()-Clopidogrel hydrochloride C16H16NO2SCl.HCl [130209-90-4]

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Alternative Name: Plavix

Chemical Name: Methyl 2-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)-2-(2-chlorophenyl)acetate hydrochloride

Biological Activity

Selective, high affinity P2Y12 receptor antagonist (pKi = 6.9 for hP2Y12 receptor). Inhibits ADP-induced platelet aggregation; potent antithrombotic agent. Requires bioactivation, unlike PSB 0739 (Cat. No. 3983). (+)-Clopidogrel hydrogen sulfate (Cat. No. 1820) also available.

Technical Data

M.Wt:
358.28
Formula:
C16H16NO2SCl.HCl
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
>99 %
Storage:
Desiccate at +4°C
CAS No:
130209-90-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet

Kugelgen (2006) Pharmacological profiles of cloned mammalian P2Y-receptor subtypes. Pharmacol.Ther. 110 415. PMID: 16257449.

Savi and Herbert (2005) Clopidogrel and ticlopidine: P2Y12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis. Semin.Thromb.Haemostas. 31 174.

Savi et al (2001) P2Y12, a new platelet ADP receptor, target of clopidogrel. Biochem.Biophys.Res.Comm. 283 379.

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Keywords: ()-Clopidogrel hydrochloride, supplier, Selective, P2Y12, antagonists, Receptors, Purinergic, purinoceptors, p2yt, Tocris Bioscience, Purinergic (P2Y) Receptor Antagonist products

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