Cat. No. 0568
Chemical Name: 1-(1-(3-Isothiocyanato)phenyl)cyclo
Biological ActivityAcylator of PCP and σ-receptors.
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All Tocris products are intended for laboratory research use only.
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Reith et al (1991) Effect of metaphit on dopaminergic neurotransmission in rat striatal slices: involvement of the dopamine transporter and voltage-dependent sodium channel. J.Pharmacol.Exp.Ther. 259 1188. PMID: 1662274.
Debler et al (1989) Metaphit, an isothiocyanate analog of PCP, induces audiogenic seizures in mice. Eur.J.Pharmacol. 165 155. PMID: 2548879.
Contreras et al (1986) Metaphit, an acylating ligand for phencyclidine receptors: characterization of in vivo actions in the rat. J.Pharmacol.Exp.Ther. 238 1101. PMID: 3018219.
Rafferty et al (1985) A specific acylating agent for the [3H]-phencyclidine receptors in rat brain. FEBS Lett. 181 318. PMID: 2982662.
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Keywords: Metaphit, supplier, Acylator, PCP, σ, sigma, receptors, Tocris Bioscience, Sigma-Related products
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