Metaphit

Cat. No. 0568

Metaphit C18H24N2S [96316-00-6]

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Chemical Name: 1-(1-(3-Isothiocyanato)phenyl)cyclohexylpiperidine

Biological Activity

Acylator of PCP and σ-receptors.

Technical Data

M.Wt:
300.46
Formula:
C18H24N2S
Solubility:
Soluble to 20 mM in ethanol with gentle warming and to 20 mM in DMSO with gentle warming
Storage:
Desiccate at -20°C
CAS No:
96316-00-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Certificate of Analysis is currently unavailable
on-line. Please contact Customer Service

Reith et al (1991) Effect of metaphit on dopaminergic neurotransmission in rat striatal slices: involvement of the dopamine transporter and voltage-dependent sodium channel. J.Pharmacol.Exp.Ther. 259 1188. PMID: 1662274.

Debler et al (1989) Metaphit, an isothiocyanate analog of PCP, induces audiogenic seizures in mice. Eur.J.Pharmacol. 165 155. PMID: 2548879.

Contreras et al (1986) Metaphit, an acylating ligand for phencyclidine receptors: characterization of in vivo actions in the rat. J.Pharmacol.Exp.Ther. 238 1101. PMID: 3018219.

Rafferty et al (1985) A specific acylating agent for the [3H]-phencyclidine receptors in rat brain. FEBS Lett. 181 318. PMID: 2982662.

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Keywords: Metaphit, supplier, Acylator, PCP, σ, sigma, receptors, Tocris Bioscience, Sigma-Related products

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