Cat. No. 0568
Chemical Name: 1-(1-(3-Isothiocyanato)phenyl)cyclo
Biological ActivityAcylator of PCP and σ-receptors.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
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References are publications that support the products' biological activity.
Reith et al (1991) Effect of metaphit on dopaminergic neurotransmission in rat striatal slices: involvement of the dopamine transporter and voltage-dependent sodium channel. J.Pharmacol.Exp.Ther. 259 1188. PMID: 1662274.
Debler et al (1989) Metaphit, an isothiocyanate analog of PCP, induces audiogenic seizures in mice. Eur.J.Pharmacol. 165 155. PMID: 2548879.
Contreras et al (1986) Metaphit, an acylating ligand for phencyclidine receptors: characterization of in vivo actions in the rat. J.Pharmacol.Exp.Ther. 238 1101. PMID: 3018219.
Rafferty et al (1985) A specific acylating agent for the [3H]-phencyclidine receptors in rat brain. FEBS Lett. 181 318. PMID: 2982662.
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Citations are publications that use Tocris products.
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Keywords: Metaphit, supplier, Acylator, PCP, σ, sigma, receptors, Tocris Bioscience, Sigma-Related products