(±)-AC 7954 hydrochloride
Cat. No. 2484
Chemical Name: (±)-3-(4-Chlorophenyl)-3-[2-(dimethy
Biological ActivityHighly selective, non-peptide urotensin-II (UT) receptor agonist that displays potent activity at human and rat UT receptors (pEC50 values are 6.5 and 6.7 respectively).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Lehmann et al (2006) Novel potent and efficacious nonpeptidic urotensin II receptor agonists. J.Med.Chem. 49 2232. PMID: 16570919.
Lavecchia et al (2005) Architecture of the human urotensin II receptor: comparison of the binding domains of peptide and non-peptide urotensin II agonists. J.Med.Chem. 48 2480. PMID: 15801838.
Croston et al (2002) Discovery of the first nonpeptide agonist of the GPR14/urotensin-II receptor: 3-(4-chlorophenyl)-3-(2-(dimethylamino)ethyl)isochroman-1-one (AC-7954). J.Med.Chem. 45 4950. PMID: 12408704.
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Keywords: (±)-AC 7954 hydrochloride, supplier, Non-peptide, UT, receptor, agonists, Receptors, Urotensin-II, (±)-AC7954, hydrochloride, Tocris Bioscience, Urotensin-II Receptor Agonist products
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