CCK Octapeptide, sulfated

Cat. No. 1166

CCK Octapeptide, sulfated Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2

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Alternative Names: Cholecystokinin Octapeptide, sulfated, CCK-8

Biological Activity

Endogenous C-terminal octapeptide of CCK found in the central nervous system and gastrointestinal tract. Non-sulfated CCK Octapeptide (Cat. No. 1150) also available.

Technical Data

M.Wt:
1142.2
Formula:
C49H62N10O16S3
Sequence:
DYMGWMDF

(Modifications: Tyr-2 = SO3H, Phe-8 = C-terminal amide)

Solubility:
Soluble to 0.50 mg/ml in PBS (pH 7.4)
Storage:
Desiccate at -20°C
CAS No:
25126-32-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Certificate of Analysis / Product Datasheet
Select another batch:

Wank (1998) G-protein-coupled receptors in gastrointestinal physiology. I. CCK receptors: an exemplary family. Am.J.Physiol. 274 G607. PMID: 9575840.

Beinfel (1997) CCK biosynthesis and processing: recent progress and future challenges. Life Sci. 61 2359. PMID: 9399627.

Gaw et al (1995) Characterization of the receptors and mechanisms involved in the cardiovascular actions of sCCK-8 in the pithed rat. Br.J.Pharmacol. 115 660. PMID: 7582487.

Heinemann et al (1995) Mediation by CCKB receptors of the CCK-evoked hyperaemia in rat gastric mucosa. Br.J.Pharmacol. 116 2274. PMID: 8564259.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for CCK Octapeptide, sulfated include:

D'Agostino et al (2016) Appetite controlled by a cholecystokinin nucleus of the solitary tract to hypothalamus neurocircuit. Regul Pept 5. PMID: 26974347.

Reidelberger et al (2014) Role of capsaicin-sensitive peripheral sensory neurons in anorexic responses to intravenous infusions of cholecystokinin, peptide YY-(3-36), and glucagon-like peptide-1 in rats. Am J Physiol Endocrinol Metab 307 E619. PMID: 25117406.

Wu et al (2014) Role of cholecystokinin in anorexia induction following oral exposure to the 8-ketotrichothecenes deoxynivalenol, 15-acetyldeoxynivalenol, 3-acetyldeoxynivalenol, fusarenon X, and nivalenol. Toxicol Sci 138 278. PMID: 24385417.

Gamble et al (2013) Plasminogen activator inhibitor (PAI)-1 suppresses inhibition of gastric emptying by cholecystokinin (CCK) in mice. J Neuroendocrinol 185 41518. PMID: 23816469.

Caquineau et al (2010) Effects of cholecystokinin in the supraoptic nucleus and paraventricular nucleus are negatively modulated by leptin in 24-h fasted lean male rats. Autophagy 22 446. PMID: 20163516.

Do you know of a great paper that uses CCK Octapeptide, sulfated from Tocris? If so please let us know.show all ▼show less ▲

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Keywords: CCK Octapeptide, sulfated, supplier, C-terminal, octapeptide, CCK, Cholecystokinin, Non-Selective, Receptors, agonists, CCK-8, CCK8, Tocris Bioscience, Non-selective CCK Agonist products

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