LY 231617

Cat. No. 1286

LY 231617 C17H29NO.HCl [141545-89-3]

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Chemical Name: 2,6-bis(1,1-Dimethylethyl)-4-[(ethylamino)methyl]phenol hydrochloride

Biological Activity

Antioxidant; protects against ischemia-induced neuronal damage in rat models of global and focal cerebral ischemia. Neuroprotective in vitro and in vivo.

Technical Data

Soluble to 100 mM in DMSO and to 100 mM in ethanol
>98 %
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Fuson et al (1999) Characterization of LY 231617 protection against hydrogen peroxide toxicity. J.Neurochem. 72 1154. PMID: 10037488.

O'Neill et al (1997) Neuroprotective effects of the antioxidant LY 231617 and NO synthase inhibitors in global ischaemia. Brain Res. 760 170. PMID: 9237532.

Clemens et al (1993) The antioxidant LY 231617 reduces global ischemic neuronal injury in rats. Stroke 24 716. PMID: 8488528.

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Citations are publications that use Tocris products.

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Keywords: LY 231617, supplier, LY231617, antioxidants, anti-oxidants, neuroprotective, ischaemia-induced, neuronal, damage, global, cerebral, ischemia, neuroprotective, Tocris Bioscience, Antioxidant products

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