Endothelin 2 (human)
Cat. No. 1164
Alternative Name: ET-2
Biological ActivityEndogenous peptide found predominately in the kidney and intestine. Displays similar selectivity for ETA and ETB endothelin receptors.
(Modifications: Disulfide bridge between 1 - 15, 3 - 11)
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Servitja et al (1998) Involvement of ETA and ETB receptors in the activation of phospholipase D by endothelins in cultured rat cortical astrocytes. Br.J.Pharmacol. 124 1728. PMID: 9756390.
Inoue et al (1989) The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Proc.Natl.Acad.Sci.U.S.A. 86 2863. PMID: 2649896.
Yanagisawa and Masaski (1989) Molecular biology and biochemistry of the endothelins. TiPS 10 374. PMID: 2690429.
If you know of a relevant reference for Endothelin 2 (human) please let us know.
Citations are publications that use Tocris products. Selected citations for Endothelin 2 (human) include:
Khan et al (2006) Pharmacological characterization of endothelin receptors-mediated contraction in the mouse isolated proximal and distal colon. Br J Pharmacol 147 607. PMID: 16432510.
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Keywords: Endothelin 2 (human), supplier, ETA/ETB, agonist, Endothelin, Non-Selective, ET, Receptors, Endothelin2, (human), Tocris Bioscience, Non-selective Endothelin Agonist products
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High affinity dual ETA and ETB receptor antagonist;orally bioavailable
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