Cat. No. 0640
Chemical Name: Tropanyl 3,5-dichlorobenzoate
Biological Activity5-HT3 antagonist.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Richardson and Engel (1986) The pharmacology and function of 5-HT3 receptors. Trends Neurosci. 9 424.
Fozard (1984) MDL 72222: a potent and highly selective antagonist at neuronal 5-hydroxytryptamine receptors. Naunyn Schmiedebergs Arch.Pharmacol. 326 36. PMID: 6472484.
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Citations are publications that use Tocris products. Selected citations for MDL 72222 include:
Bocchio et al (2015) Increased serotonin transporter expression reduces fear and recruitment of parvalbumin interneurons of the amygdala. Neuropsychopharmacology 40 3015. PMID: 26052039.
Woo et al (2007) Neuregulin-1 enhances depolarization-induced GABA release. Neuron 54 599. PMID: 17521572.
Do you know of a great paper that uses MDL 72222 from Tocris? If so please let us know.
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Keywords: MDL 72222, supplier, 5-HT3, antagonists, Serotonin, Receptors, MDL72222, Tocris Bioscience, 5-HT3 Receptor Antagonist products