Maprotiline hydrochloride

Cat. No. 0935

Maprotiline hydrochloride C20H23N.HCl [10347-81-6]

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Chemical Name: 1-(3-Methylaminopropyl)dibenzo[b,e]bicyclo[2.2.2]octadiene hydrochloride

Biological Activity

Selective noradrenalin re-uptake inhibitor.

Technical Data

Soluble to 10 mM in ethanol and to 10 mM in water
>99 %
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Rodgers et al (1997) Behavioural effects in mice of subchronic chlordiazepoxide, maprotiline and fluvoxamine. II. The elevated plus-maze. Pharmacol.Biochem.Behav. 57 127. PMID: 9164563.

Pawlowski and Nowak (1987) Biochemical and pharmacological tests for the prediction of ability of monoamine uptake blockers to inhibit the uptake of noradrenaline in-vivo: the effects of desipramine, maprotiline, femoxetine and citalopram. J.Pharm.Pharmacol. 39 1003. PMID: 2894425.

Pinder et al (1977) Maprotiline: A review of its pharmacological properties and therapeutic efficacy in mental depressive states. Drugs 13 321. PMID: 326531.

Merck Index 11 5633.

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