Triacsin C

Cat. No. 2472

Triacsin C C11H17N3O [76896-80-5]

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Chemical Name: (2E,4E,7E)-2,4,7-Undecatrienal nitrosohydrazone

Biological Activity

Inhibitor of acyl-CoA synthetase. Inhibits lipid synthesis and cell proliferation in Raji lymphoma cells. Induces apoptosis in cancer cell lines and inhibits human lung cancer cell xenograft tumor growth in mice.

Technical Data

M.Wt:
207.27
Formula:
C11H17N3O
Solubility:
Soluble to 25 mM in DMSO
Purity:
>95 %
Storage:
Store at -20°C
CAS No:
76896-80-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Mashima et al (2005) p53-defective tumors with a functional apoptosome-mediated pathway: a new therapeutic target. J.Natl.Cancer.Inst. 97 765. PMID: 15900046.

Tomoda et al (1991) Evidence for an essential role of long chain acyl-CoA synthetase in animal cell proliferation. Inhibition of long chain acyl-CoA synthetase by triacsins caused inhibition of Raji cell proliferation. J.Biol.Chem. 266 4214. PMID: 1999415.

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Keywords: Triacsin C, supplier, Triacsin, C, inhibitors, inhibits, acyl-coa-synthetase, antitumor, Tocris Bioscience, Other Synthase/Synthetase Inhibitor products

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