Daidzein

Cat. No. 1417

Daidzein C15H10O4 [486-66-8]

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Chemical Name: 7-Hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Biological Activity

Analog of the phytoestrogen genistein (Cat. No. 1110). Blocks G1 phase cell cycle progression. Agonist at estrogen receptors.

Technical Data

M.Wt:
254.24
Formula:
C15H10O4
Solubility:
Soluble to 100 mM in DMSO
Purity:
>99 %
Storage:
Desiccate at -20°C
CAS No:
486-66-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Casanova et al (1999) Development effects of dietary phytoestrogens in Sprague Dawley rats and interactions of genistein and daidzein with rat estrogen receptors α and β in vitro. Toxicol.Sci. 51 236. PMID: 10543025.

Higashi and Ogawara (1994) Daidzein inhibits insulin- or insulin-like growth factor-1-mediated signaling in cell cycle progression of Swiss 3T3 cells. Biochim.Biophys.Acta 1221 29. PMID: 8130274.

Jing et al (1993) Differentiation of promyelocytic leukemia cells HL-60 induced by daidzein in vitro and in vivo. Anticancer Res. 13 1049. PMID: 8352524.

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Keywords: Daidzein, supplier, Arrests, cell, cycle, G1, phase, Estrogen, receptor, agonists, induces, arrest, Cell, Cycle, inhibitors, inhibits, ER, ERR, Receptors, Tocris Bioscience, Cell Cycle Inhibitor products

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