Cat. No. 2470
Alternative Names: Flogovital, Aulin
Chemical Name: N-(4-Nitro-2-phenoxyphenyl)methanes
Biological ActivitySelective, orally active cyclooxygenase-2 (COX-2) inhibitor. Produces potent analgesic, anti-inflammatory and antipyretic activities in vivo. Reported to produce fewer gastrointestinal side effects than standard NSAIDs. .
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Cullen et al (1998) Selective cyclooxygenase-2 inhibition by nimesulide in man. J.Pharmacol.Exp.Ther. 287 578. PMID: 9808683.
Famaey (1997) In vitro and in vivo pharmacological evidence of selective cyclooxygenase-2 inhibition by nimesulide: an overview. Inflamm.Res. 46 437. PMID: 9427063.
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Citations are publications that use Tocris products. Selected citations for Nimesulide include:
Staniaszek et al (2010) Effects of COX-2 inhibition on spinal nociception: the role of endocannabinoids. Br J Pharmacol 160 669. PMID: 20590570.
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Keywords: Nimesulide, supplier, Cyclooxygenase-2, COX-2, inhibitors, Cyclooxygenase, Oxygenases, Oxidases, Tocris Bioscience, Cyclooxygenase Inhibitor products
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