Cat. No. 2470
Alternative Names: Flogovital, Aulin
Chemical Name: N-(4-Nitro-2-phenoxyphenyl)methanes
Biological ActivitySelective, orally active cyclooxygenase-2 (COX-2) inhibitor. Produces potent analgesic, anti-inflammatory and antipyretic activities in vivo. Reported to produce fewer gastrointestinal side effects than standard NSAIDs. .
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Cullen et al (1998) Selective cyclooxygenase-2 inhibition by nimesulide in man. J.Pharmacol.Exp.Ther. 287 578. PMID: 9808683.
Famaey (1997) In vitro and in vivo pharmacological evidence of selective cyclooxygenase-2 inhibition by nimesulide: an overview. Inflamm.Res. 46 437. PMID: 9427063.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products. Selected citations for Nimesulide include:
Staniaszek et al (2010) Effects of COX-2 inhibition on spinal nociception: the role of endocannabinoids. Br J Pharmacol 160 669. PMID: 20590570.
Do you know of a great paper that uses Nimesulide from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Nimesulide, supplier, Cyclooxygenase-2, COX-2, inhibitors, inhibits, Cyclooxygenase, Oxygenases, Oxidases, Tocris Bioscience, Cyclooxygenase Inhibitor products
Find multiple products by catalog number
New Products in this Area
Selective myeloperoxidase (MPO) inhibitorINCB 024360-analog
Potent indoleamine 2,3-dioxygenase (IDO) inhibitorLM 10
Selective tryptophan 2,3-dioxygenase (TDO) inhibitorNoxA1ds
Potent and selective NADPH oxidase 1 (NOX1) inhibitor
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.