S-Isopropylisothiourea hydrobromide

Cat. No. 0897

S-Isopropylisothiourea hydrobromide C4H10N2S.HBr [4269-97-0]

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Biological Activity

Potent inhibitor of NO synthase, with selectivity for the inducible form.

Technical Data

Soluble to 100 mM in DMSO
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Moore and Handy (1997) Selective inhibitors of neuronal nitric oxide synthase - is no NOS really good NOS for the nervous system? TiPS 18 204. PMID: 9226999.

Handy et al (1995) Effect of S-methylisothiourea on neuronal nitric oxide synthase, nociception and blood pressure in the mouse. Br.J.Pharmacol. 115 68P.

Garvey et al (1994) Potent and selective inhibition of human nitric oxide synthases. J.Biol.Chem. 269 26669. PMID: 7523409.

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Citations are publications that use Tocris products.

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Keywords: S-Isopropylisothiourea hydrobromide, supplier, iNOS, inhibitors, inhibits, arginine, binding, site, Nitric, Oxide, Signaling, Signalling, Inducible, NO, Synthases, Tocris Bioscience, iNOS Inhibitor products

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