Cat. No. 2447
Chemical Name: 6-Amino-N-cyclohexyl-3-methylthiazo
Biological ActivityDerivative of the mGlu1-selective antagonist YM 298198 (Cat. No. 2448).
Licensing InformationSold with the permission of Astellas Pharma Inc.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Kohara et al (2005) Radioligand binding properties and pharmacological characterization of 6-Amino-N-cyclohexyl-N,3-dimethyl-thiazolo[3,2-a]-benzimidazole-2-carboxamide (YM-298198), a high-affinity, selective and noncompetitive antagonist of metabotropic glutamate receptor type 1. J.Pharmacol.Exp.Ther. 315 163. PMID: 15976016.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses Desmethyl-YM 298198 from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Desmethyl-YM 298198, supplier, Derivative, mGlu1, mGluR1, antagonists, YM, 298198, Group, I, Receptors, Glutamate, Metabotropic, Desmethyl-YM298198, Tocris Bioscience, Glutamate (Metabotropic) Group I Receptor Antagonist products
Find multiple products by catalog number
New Products in this Area
Negative allosteric modulator at mGlu7; brain penetrantVU 0409551
Selective mGlu5 positive allosteric modulator; brain penetrant and orally bioavailable
Follow Tocris on LinkedIn
Visit our LinkedIn page for the latest Tocris news, events and updates.