Desmethyl-YM 298198

Cat. No. 2447

Desmethyl-YM 298198 C17H20N4OS.HCl [1177767-57-5]

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Chemical Name: 6-Amino-N-cyclohexyl-3-methylthiazolo[3,2-a]benzimidazole-2-carboxamide hydrochloride

Biological Activity

Derivative of the mGlu1-selective antagonist YM 298198 (Cat. No. 2448).

Licensing Information

Sold with the permission of Astellas Pharma Inc.

Technical Data

M.Wt:
364.89
Formula:
C17H20N4OS.HCl
Solubility:
Soluble to 50 mM in DMSO
Purity:
>98 %
Storage:
Desiccate at RT
CAS No:
1177767-57-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Kohara et al (2005) Radioligand binding properties and pharmacological characterization of 6-Amino-N-cyclohexyl-N,3-dimethyl-thiazolo[3,2-a]-benzimidazole-2-carboxamide (YM-298198), a high-affinity, selective and noncompetitive antagonist of metabotropic glutamate receptor type 1. J.Pharmacol.Exp.Ther. 315 163. PMID: 15976016.

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Citations are publications that use Tocris products.

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Keywords: Desmethyl-YM 298198, supplier, Derivative, mGlu1, mGluR1, antagonists, YM, 298198, Group, I, Receptors, Glutamate, Metabotropic, Desmethyl-YM298198, Tocris Bioscience, Glutamate (Metabotropic) Group I Receptor Antagonist products

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