Cat. No. 2446
Chemical Name: Ammonium trichloro[1,2-ethanediolato-O,O']-te
Biological ActivityImmunomodulator; inhibits IL-10 synthesis and potentiates IL-1α, IL-2 and TNF-α release.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Kalechman et al (2004) Inhibition of interleukin-10 by the immunomodulator AS101 reduces mesangial cell proliferation in experimental mesangioproliferative glomerulonephritis. J.Biol.Chem. 279 24724. PMID: 15001575.
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Citations are publications that use Tocris products. Selected citations for AS 101 include:
Souza-Fonseca-Guimaraes et al (2012) NK cell tolerance to TLR agonists mediated by regulatory T cells after polymicrobial sepsis. J Immunol 188 5850. PMID: 22566566.
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Keywords: AS 101, supplier, Immunomodulators, inhibits, inhibitors, IL-10, synthesis, potentiates, IL-1alpha, IL-2, TNFalpha, release, TNF-α, TNF-alpha, Interleukins, Tumor, Necrosis, Factor-α, Factor-alpha, Cytokines, Cytokine, NF-κB, NF-kappaB, Signaling, Signalling, AS101, Tocris Bioscience, Cytokine products