AS 101

Cat. No. 2446

AS 101 C2H4Cl3O2Te.NH4 [106566-58-9]

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Chemical Name: Ammonium trichloro[1,2-ethanediolato-O,O']-tellurate

Biological Activity

Immunomodulator; inhibits IL-10 synthesis and potentiates IL-1α, IL-2 and TNF-α release.

Technical Data

M.Wt:
312.05
Formula:
C2H4Cl3O2Te.NH4
Solubility:
Soluble to 5 mM in DMSO with gentle warming and to 5 mM in ethanol with gentle warming
Storage:
Desiccate at RT
CAS No:
106566-58-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Kalechman et al (2004) Inhibition of interleukin-10 by the immunomodulator AS101 reduces mesangial cell proliferation in experimental mesangioproliferative glomerulonephritis. J.Biol.Chem. 279 24724. PMID: 15001575.

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Citations are publications that use Tocris products. Selected citations for AS 101 include:

Souza-Fonseca-Guimaraes et al (2012) NK cell tolerance to TLR agonists mediated by regulatory T cells after polymicrobial sepsis. J Immunol 188 5850. PMID: 22566566.

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Keywords: AS 101, supplier, Immunomodulators, inhibits, inhibitors, IL-10, synthesis, potentiates, IL-1alpha, IL-2, TNFalpha, release, TNF-α, TNF-alpha, Interleukins, Tumor, Necrosis, Factor-α, Factor-alpha, Cytokines, Cytokine, NF-κB, NF-kappaB, Signaling, Signalling, AS101, Tocris Bioscience, Cytokine products

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