Cat. No. 0544
Chemical Name: 1-(4-Iodophenyl)-3-(2-adamantyl)gua
Biological ActivityPotent σ-receptor antagonist.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Whittemore et al (1997) Antagonism of N-methyl-D-aspartate receptors by σ site ligands: potency, subtype-selectivity and mechanisms of inhibition. J.Pharmacol.Exp.Ther. 282 326. PMID: 9223571.
Wilson et al (1991) Radiosynthesis of σ receptor ligands for positron emission tomography: 11C- and 18F-labelled guanidines. J.Med.Chem. 34 1867. PMID: 1648140.
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Citations are publications that use Tocris products. Selected citations for IPAG include:
Kim et al (2012) Inhibition of tumor cell growth by Sigma1 ligand mediated translational repression. Biochem Biophys Res Commun 426 177. PMID: 22925888.
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Keywords: IPAG, supplier, Potent, σ, sigma, antagonists, General, Receptors, Tocris Bioscience, Sigma-Related Antagonist products