IPAG

Cat. No. 0544

IPAG C17H22IN3 [193527-91-2]

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Chemical Name: 1-(4-Iodophenyl)-3-(2-adamantyl)guanidine

Biological Activity

Potent σ-receptor antagonist.

Technical Data

M.Wt:
395.29
Formula:
C17H22IN3
Solubility:
Soluble to 50 mM in ethanol and to 100 mM in DMSO
Purity:
>98 %
Storage:
Store at RT
CAS No:
193527-91-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

Whittemore et al (1997) Antagonism of N-methyl-D-aspartate receptors by σ site ligands: potency, subtype-selectivity and mechanisms of inhibition. J.Pharmacol.Exp.Ther. 282 326. PMID: 9223571.

Wilson et al (1991) Radiosynthesis of σ receptor ligands for positron emission tomography: 11C- and 18F-labelled guanidines. J.Med.Chem. 34 1867. PMID: 1648140.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for IPAG include:

Kim et al (2012) Inhibition of tumor cell growth by Sigma1 ligand mediated translational repression. Biochem Biophys Res Commun 426 177. PMID: 22925888.

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Keywords: IPAG, supplier, Potent, σ, sigma, antagonists, General, Receptors, Tocris Bioscience, Sigma-Related Antagonist products

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