(1R,1'S,3'R/1R,1'R,3'S)-L-054,264

Cat. No. 2444

(1R,1S,3R/1R,1R,3'S)-L-054,264 C33H41N5O2 [208706-12-1]

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Chemical Name: N-[(1R)-2-[[[(1S*,3R*)-3-(Aminomethyl)cyclohexyl]methyl]amino]-1-(1H-indol-3-ylmethyl)-2-oxoethyl]spiro[1H-indene-1,4'-piperidine]-1'-carboxamide

Biological Activity

Potent and selective somatostatin sst2 receptor agonist (Ki values are 4, 537, 2480, 3614 and 5017 nM for cloned human sst2, sst1, sst4, sst3 and sst5 receptors respectively).

Technical Data

M.Wt:
539.71
Formula:
C33H41N5O2
Solubility:
Soluble to 50 mM in DMSO and to 100 mM in ethanol
Purity:
>96 %
Storage:
Store at +4°C
CAS No:
208706-12-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Yang et al (1998) Spiro[1H-indene-1,4'-piperidine] derivatives as potent and selective non-peptide human somatostatin receptor subtype 2 (sst2) agonists. J.Med.Chem. 41 2175. PMID: 9632348.

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Keywords: (1R,1S,3R/1R,1R,3'S)-L-054,264, supplier, Potent, selective, sst2, agonists, sst, Receptors, Somatostatin, (1R,1S,3R/1R,1R,3S)-L-054,264, L054264, Tocris Bioscience, Somatostatin (sst) Receptor Agonist products

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