Cat. No. 2841
Alternative Name: Diferuloylmethane
Chemical Name: (1E,6E)-1,7-Bis(4-hydroxy-3-methoxy
Biological ActivityAntitumor, anti-inflammatory and antioxidant agent. Downregulates expression of reactive-oxygen-generating enzymes (cyclooxygenase, lipoxygenase, iNOS), TNFα, IL-1, IL-6, PKC, EGFR, NF-κB, IκB kinase and more. Upregulates expression of PPARγ, p53, Nrf2. Also displays antimicrobial, antidiabetic neuro- and cardioprotective properties in vivo.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Aggarwal and Sung (2009) Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets. TiPS 30 85. PMID: 19110321.
Cole et al (2007) Neuroprotective effects of curcumin. Adv.Exp.Med.Biol. 595 197. PMID: 17569212.
Kuttan et al (2007) Antitumour, anti-invasion, and antimetastatic effects of curcumin. Adv.Exp.Med.Biol. 595 173. PMID: 17569210.
Lin (2007) Molecular targets of curcumin. Adv.Exp.Med.Biol. 595 227. PMID: 17569214.
Miriyala et al (2007) Cardioprotective effects of curcumin. Adv.Exp.Med.Biol. 595 359. PMID: 17569220.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses Curcumin from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: Curcumin, supplier, Antitumor, anti-inflammatory, antioxidant, Apoptosis, Inducer, nrf2, Tocris Bioscience, Apoptosis Inducing products
Find multiple products by catalog number
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.