ICI 204,448 hydrochloride
Cat. No. 0822
Chemical Name: (RS)-[3-[1-[[(3,4-Dichlorophenyl)ac
Biological ActivityPeripherally acting κ agonist.
Licensing InformationSold with the permission of AstraZeneca UK Ltd.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Ke´ta et al (1995) Antinociceptive effect of a κ-opioid receptor agonist that minimally crosses the blood-brain barrier (ICI 204448) in a rat model of mononeuropathy. Eur.J.Pharmacol. 277 275. PMID: 7493620.
Shaw et al (1989) ICI-204,448: a κ-opioid agonist with limited access to the CNS. Br.J.Pharmacol. 96 986. PMID: 2568146.
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