ICI 185,282

Cat. No. 0836

ICI 185,282
 C18H21F3O5 [106393-80-0]

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Chemical Name: 5-(Z)-7-(4-o-Hydroxyphenyl-2-trifluoromethyl-1,3 dioxan-cis-5-yl)heptenoic acid

Biological Activity

Potent thromboxane receptor antagonist.

Licensing Information

Sold with the permission of AstraZeneca UK Ltd.

Technical Data

M.Wt:
374.36
Formula:
C18H21F3O5
Solubility:
Soluble in DMSO
Storage:
Desiccate at -20°C
CAS No:
106393-80-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

Certificate of Analysis is currently unavailable
on-line. Please contact Customer Service

References are publications that support the products' biological activity.

Birch et al (1988) Studies in the guinea-pig with ICI 185,282: a thromboxane A2 receptor antagonist. J.Pharm.Pharmacol. 40 706. PMID: 2907537.

If you know of a relevant reference for ICI 185,282 please let us know.

Citations are publications that use Tocris products. Selected citations for ICI 185,282 include:

Kleinbongard et al (2011) Vasoconstrictor potential of coronary aspirate from patients undergoing stenting of saphenous vein aortocoronary bypass grafts and its pharmacological attenuation. Circ Res 108 344. PMID: 21183739.

Do you know of a great paper that uses ICI 185,282 from Tocris? If so please let us know.

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Keywords: ICI 185,282, supplier, Potent, thromboxane, A2, TXA2, receptors, antagonists, TP, Prostanoid, prostaglandins, prostacyclins, eicosanoids, ICI185282, AstraZeneca, Tocris Bioscience, Prostanoid Receptor Antagonist products

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