ICI 162,846

Cat. No. 0833

ICI 162,846 C11H17F3N6O [84545-30-2]

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Chemical Name: N-[1-(4-Carboxamidobutyl)-1H-pyrazol-3-yl)]-N'-(2,2,2-trifluoroethyl)guanidine

Biological Activity

A potent histamine H2 receptor antagonist.

Licensing Information

Sold with the permission of AstraZeneca UK Ltd.

Technical Data

M.Wt:
306.29
Formula:
C11H17F3N6O
Solubility:
Soluble in ethanol and to 100 mM in DMSO
Storage:
Store at RT
CAS No:
84545-30-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Certificate of Analysis is currently unavailable
on-line. Please contact Customer Service

Gompertz et al (1991) Acid blockade by omeprazole or ICI 162846 in a chronic duodenal ulcer model. Agents Actions 33 161. PMID: 1716826.

Streett et al (1988) Morphological stomach findings in rats and mice treated with the H2 receptor antagonists, ICI 125,211 and ICI 162,846. Toxicol.Pathol. 16 299. PMID: 2903545.

Wilson et al (1986) Inhibition of human gastric secretion by ICI 162,846 - a new histamine H2 receptor antagonist. Br.J.Clin.Pharmacol. 21 685. PMID: 2874823.

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Keywords: ICI 162,846, supplier, Potent, H2, antagonists, active, vivo, Receptors, Histamine, histaminergic, ICI162846, AstraZeneca, Tocris Bioscience, Histamine H2 Receptor Antagonist products

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