ICI 154,129

Cat. No. 0827

ICI 154,129 N,N-diallyl-Tyr-Gly-ψ-(CH2S)-Phe-Leu-OH

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Biological Activity

Selective δ opioid antagonist.

Licensing Information

Sold with the permission of AstraZeneca UK Ltd.

Technical Data

M.Wt:
638.83
Formula:
C34H46N4O6S
Sequence:
YGFL

(Modifications: Tyr-1 = N,N-diallyl-Tyr, Gly-2 - Phe-3 peptide bond replaced with Psi-(CH2S))

Solubility:
Soluble to 1 mg/ml in methanol
Storage:
Desiccate at -20°C
CAS No:
83420-94-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Certificate of Analysis is currently unavailable
on-line. Please contact Customer Service

Rees and Hunter (1990) Opioid Receptors. Comprehensive Medicinal Chemistry. Ed. Hansch. 3 805.

Shaw et al (1982) Selective antagonists at the opiate delta-receptor. Life Sci. 31 1259. PMID: 6128652.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for ICI 154,129 include:

Jiang et al (2015) Analgesic roles of peripheral intrinsic met-enkephalin and dynorphin A in long-lasting inflammatory pain induced by complete Freund's adjuvant in rats. J Pharmacol Exp Ther 9 2344. PMID: 26136984.

Do you know of a great paper that uses ICI 154,129 from Tocris? If so please let us know.

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Keywords: ICI 154,129, supplier, δ-opioid, delta-opioid, selective, peptide, antagonists, DOP, Receptors, OP1, ICI154129, AstraZeneca, Tocris Bioscience, δ Opioid Receptor Antagonist products

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