LP 12 hydrochloride
Cat. No. 2925
Chemical Name: 4-(2-Diphenyl)-N-(1,2,3,4-tetrahydr
Biological Activity5-HT7 receptor agonist displaying selectivity over D2, 5-HT1A and 5-HT2A receptors (Ki values are 0.22, 7.3, 52.7 and 326 nM respectively). Induces relaxation of substance P-induced contractions in guinea pig ileum (EC50 = 1.77 μM).
Licensing InformationSold under license from the University of Bari
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Leopoldo et al (2007) Structure-activity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinehexanamides, a class of 5-HT7 receptor agents. J.Med.Chem. 50 4214. PMID: 17649988.
If you know of a relevant reference for LP 12 hydrochloride please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses LP 12 hydrochloride from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: LP 12 hydrochloride, supplier, 5-HT7, agonists, Serotonin, Receptors, 5-Hydroxytryptamine, LP12, hydrochloride, Tocris Bioscience, 5-HT7 Receptor Agonist products
Find multiple products by catalog number
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.