Amyloid β-peptide (1-40) (rat)

Cat. No. 2424

Amyloid b-peptide (1-40) (rat) Asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Glu-Val-Arg-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val

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Biological Activity

Rat form of the amyloid β-peptide found in plaques associated with Alzheimer's disease. Shown to have both neurotrophic and neurotoxic effects.

Technical Data

Soluble to 1 mg/ml in 1% Ammonia
Desiccate at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Miguel-Hidalgo and Cacabelos (1998) Beta-amyloid(1-40)-induced neurodegeneration in the rat hippocampal neurons of the CA1 subfield. Acta Neuropathol. 95 455. PMID: 9600591.

Cleary et al (1995) Beta-amyloid(1-40) effects on behavior and memory. Brain Res. 682 69. PMID: 7552329.

Kowalska and Badellino (1994) β-Amyloid protein induces platelet aggregation and supports platelet adhesion. Biochem.Biophys.Res.Comm. 205 1829.

Yankner et al (1990) Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides. Science 250 279. PMID: 2218531.

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