7-Hydroxy-PIPAT maleate

Cat. No. 0719

7-Hydroxy-PIPAT maleate C16H22INO.C4H4O4 [200722-46-9]

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Alternative Name: 7-OH-PIPAT

Chemical Name: (RS)-trans-7-Hydroxy-2-[N-propyl-N-(3'-iodo-2'-propenyl)amino]tetralin maleate

Biological Activity

This ligand has uniquely high affinity and selectivity for the D3 receptor. 8-Hydroxy-PIPAT maleate (Cat. No. 0797) also available.

Licensing Information

Sold with the permission of the University of Pennsylvania

Technical Data

M.Wt:
487.33
Formula:
C16H22INO.C4H4O4
Solubility:
Soluble to 50 mM in DMSO
Purity:
>98 %
Storage:
Desiccate at +4°C
CAS No:
200722-46-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Chumpradit et al (1993) Synthesis and optical resolution of (R)- and (S)-trans-7-hydroxy-2-[N-propyl-N-(3'-iodo-2'-propenyl)amino]tetralin: a new D3 dopamine receptor ligand. J.Med.Chem. 36 4308. PMID: 8277513.

Foulon et al (1993) Synthesis of (R,S)-2'-trans-7-hydroxy-2-[N-n-propyl-N-(3'-iodo-2'-amino]tetralin (trans-7-OH-PIPAT): a new D3 dopamine receptor ligand. J.Med.Chem. 36 1499. PMID: 8098771.

Kung et al (1993) In vitro binding of a novel dopamine D3 receptor ligand: [125I]-trans-7-OH-PIPAT. Eur.J.Pharmacol. 235 165. PMID: 8519278.

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Keywords: 7-Hydroxy-PIPAT maleate, supplier, D3, agonists, Dopamine, Receptors, dopaminergic, Tocris Bioscience, D3 Receptor Agonist products

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