Cat. No. 0719
Alternative Name: 7-OH-PIPAT
Chemical Name: (RS)-trans-7-Hydroxy-2-[N-propyl-N-
Biological ActivityThis ligand has uniquely high affinity and selectivity for the D3 receptor. 8-Hydroxy-PIPAT maleate (Cat. No. 0797) also available.
Licensing InformationSold with the permission of the University of Pennsylvania
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Chumpradit et al (1993) Synthesis and optical resolution of (R)- and (S)-trans-7-hydroxy-2-[N-propyl-N-(3'-iodo-2'-propenyl)amino]tetralin: a new D3 dopamine receptor ligand. J.Med.Chem. 36 4308. PMID: 8277513.
Foulon et al (1993) Synthesis of (R,S)-2'-trans-7-hydroxy-2-[N-n-propyl-N-(3'-iodo-2'-amino]tetralin (trans-7-OH-PIPAT): a new D3 dopamine receptor ligand. J.Med.Chem. 36 1499. PMID: 8098771.
Kung et al (1993) In vitro binding of a novel dopamine D3 receptor ligand: [125I]-trans-7-OH-PIPAT. Eur.J.Pharmacol. 235 165. PMID: 8519278.
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Keywords: 7-Hydroxy-PIPAT maleate, supplier, D3, agonists, Dopamine, Receptors, dopaminergic, Tocris Bioscience, D3 Receptor Agonist products