MRS 3777 hemioxalate

Cat. No. 2403

MRS 3777 hemioxalate C17H19N5O.C2H2O4 [1186195-57-2]

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Chemical Name: 2-Phenoxy-6-(cyclohexylamino)purine hemioxalate

Biological Activity

High affinity adenosine A3 receptor antagonist (Ki = 47 nM) that displays > 200-fold selectivity versus A1, A2A and A2B receptors.

Technical Data

M.Wt:
354.39
Formula:
C17H19N5O.½C2H2O4
Solubility:
Soluble to 50 mM in DMSO
Purity:
>98 %
Storage:
Desiccate at RT
CAS No:
1186195-57-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Jacobson and Gao (2006) Adenosine receptors as therapeutic targets. Nat.Rev.Drug Discov. 5 247. PMID: 16518376.

Moro et al (2006) Progress in the pursuit of therapeutic adenosine receptor antagonists. Med.Res.Rev. 26 131. PMID: 16380972.

Perreira et al (2005) "Reversine" and its 2-substituted adenine derivatives as potent and selective A3 adenosine receptor antagonists. J.Med.Chem. 48 4910. PMID: 16033270.

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Keywords: MRS 3777 hemioxalate, supplier, High, affinity, selective, A3, antagonists, Receptors, adenosines, MRS3777, hemioxalate, Tocris Bioscience, A3 Receptor Antagonist products

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