Cat. No. 2396
Alternative Names: Amaryl, Glimperide
Chemical Name: 3-Ethyl-2,5-dihydro-4-methyl-N-[2-[
Biological ActivityPotent Kir6 (KATP) channel blocker and anti-diabetic agent. Inhibits pinacidil-activated cardiac Kir6 channels with an IC50 of 6.8 nM.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Lawrence et al (2002) Effect of metabolic inhibition on glimepiride block of native and cloned cardiac sacrolemmal KATP channels. Br.J.Pharmacol. 136 746. PMID: 12086984.
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Keywords: Glimepiride, supplier, KATP, channels, openers, Potassium, KIR, Inward, Rectifier, K+, Kir6, Tocris Bioscience, Inward Rectifier Potassium (Kir) Channel Blocker products