Cat. No. 0706
Chemical Name: (±)-7-Hydroxy-2-dipropylaminotetrali
Biological ActivityD3 dopamine receptor agonist (Ki values are ~ 1, 10, 650 and ~ 5000 nM for D3, D2, D4 and D1 receptors respectively). (R)-(+)-8-Hydroxy-DPAT hydrobromide (Cat. No. 1080) and 8-Hydroxy-DPAT hydrobromide (Cat. No 0529) also available.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Levesque (1996) Aminotetralin drugs and D3 receptor fuctions. Biochem.Pharmacol. 52 511. PMID: 8759022.
Seeman and Van Tol (1994) Dopamine receptor pharmacology. TiPS 15 264. PMID: 7940991.
Daly and Waddington (1993) Behavioural effects of the D3 dopamine receptor agonist 7-OH-DPAT in relation to other D2-like agonists. Neuropharmacology 32 509. PMID: 8321432.
Levesque et al (1992) Identification, characterization, and localization of the dopamine D3 receptor in rat brain using [3H]-7-hydroxy-N,N-di-n-propyl-2-aminotetralin. Proc.Natl.Acad.Sci.U.S.A. 89 8155. PMID: 1518841.
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Keywords: 7-Hydroxy-DPAT hydrobromide, supplier, Dopamine, agonists, D3, Receptors, dopaminergic, Tocris Bioscience, D3 Receptor Agonist products